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Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3

dc.rights.licenseopenen_US
dc.contributor.authorRAIMUNDO, M.
dc.contributor.authorMIRA, F.
dc.contributor.authorCACHULO, M. D. L.
dc.contributor.authorBARRETO, P.
dc.contributor.authorRIBEIRO, L.
dc.contributor.authorFARINHA, C.
dc.contributor.authorLAINS, I.
dc.contributor.authorNUNES, S.
dc.contributor.authorALVES, D.
dc.contributor.authorFIGUEIRA, J.
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorMERLE, Benedicte
ORCID: 0000-0003-1332-0954
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDELCOURT, Cecile
dc.contributor.authorSANTOS, L.
dc.contributor.authorSILVA, R.
dc.date.accessioned2020-12-15T16:01:34Z
dc.date.available2020-12-15T16:01:34Z
dc.date.issued2018-12
dc.identifier.issn1755-3768 (Electronic) 1755-375X (Linking)en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/23556
dc.description.abstractEnPURPOSE: To characterize the lifestyle and nutritional risk profile associated with the Mediterranean diet in a Portuguese population with and without age-related macular degeneration (AMD). METHODS: Nested case-control study (n = 883) within the Coimbra Eye Study, including 434 subjects with AMD and 449 age- and sex-matched subjects without AMD. All enrolled subjects underwent a full risk assessment, including lifestyle-related risk factors and a thorough food frequency questionnaire. This allowed us to build an adherence score to the Mediterranean diet (mediSCORE, range 0-9) constructed from individual food intakes. Food intake was also further analysed by conversion to micronutrient consumption. RESULTS: Our results suggest that physical activity has a protective role in AMD [p = 0.018 after multivariate adjustment, OR: 0.69 (0.51-0.93)]. High (mediSCORE >/=6) was also found to be protective [p = 0.041, OR: 0.62 (95% CI: 0.38-0.97)]. Food group analysis unveiled a specific protective role for increased fruits consumption (p = 0.029). Finally, micronutrient analysis revealed a protective role associated with increased consumption of caffeine, fibres, beta-carotene, vitamin C and vitamin E (p < 0.05). CONCLUSION: High mediSCORE appears to confer protection against the development of AMD in a Mediterranean population. This effect is driven by increased consumption of fruits and some antioxidant micronutrients, which emerged as statistically significant protective factors. Further studies are required to establish dietary recommendations with clinical application.
dc.language.isoENen_US
dc.subject.enLEHA
dc.title.enAdherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3
dc.title.alternativeActa Ophthalmolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1111/aos.13775en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed30218481en_US
bordeaux.journalActa Ophthalmologicaen_US
bordeaux.pagee926-e932en_US
bordeaux.volume96en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - U1219en_US
bordeaux.issue8en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.teamLEHA_BPH
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-03193160
hal.version1
hal.date.transferred2021-04-08T13:43:24Z
hal.exporttrue
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