Multidisciplinary development of the Geriatric Core Dataset for clinical research in older patients with cancer: A French initiative with international survey
| dc.rights.license | open | en_US |
| dc.contributor.author | PAILLAUD, E. | |
| dc.contributor.author | SOUBEYRAN, P. | |
| dc.contributor.author | CAILLET, P. | |
| dc.contributor.author | CUDENNEC, T. | |
| dc.contributor.author | BRAIN, E. | |
| dc.contributor.author | TERRET, C. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | ETCHEPARE, Fanny | |
| dc.contributor.author | MOUREY, L. | |
| dc.contributor.author | APARICIO, T. | |
| dc.contributor.author | PAMOUKDJIAN, F. | |
| dc.contributor.author | AUDISIO, R. A. | |
| dc.contributor.author | ROSTOFT, S. | |
| dc.contributor.author | HURRIA, A. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | BELLERA, Carine | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | MATHOULIN-PELISSIER, Simone | |
| dc.date.accessioned | 2020-12-14T09:29:20Z | |
| dc.date.available | 2020-12-14T09:29:20Z | |
| dc.date.issued | 2018-11 | |
| dc.identifier.issn | 1879-0852 (Electronic) 0959-8049 (Linking) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/21427 | |
| dc.description.abstractEn | BACKGROUND: To define a core set of geriatric data to be methodically collected in clinical cancer trials of older adults, enabling comparison across trials. PATIENTS AND METHODS: Following a consensus approach, a panel of 14 geriatricians from oncology clinics identified seven domains of importance in geriatric assessment. Based on the international recommendations, geriatricians selected the mostly commonly used tools/items for geriatric assessment by domain (January-October 2015). The Geriatric Core Dataset (G-CODE) was progressively developed according to RAND appropriateness ratings and feedback during three successive Delphi rounds (July-September 2016). The face validity of the G-CODE was assessed with two large panels of health professionals (55 national and 42 international experts) involved both in clinical practice and cancer trials (March-September 2017). RESULTS AND DISCUSSION: After the last Delphi round, the tools/items proposed for the G-CODE were the following: (1) social assessment: living alone or support requested to stay at home; (2) functional autonomy: Activities of Daily Living (ADL) questionnaire and short instrumental ADL questionnaire; (3) mobility: Timed Up and Go test; (4) nutrition: weight loss during the past 6 months and body mass index; (5) cognition: Mini-Cog test; (6) mood: mini-Geriatric Depression Scale and (7) comorbidity: updated Charlson Comorbidity Index. More than 70% of national experts (42 from 20 cities) and international experts (31 from 13 countries) participated. National and international surveys showed good acceptability of the G-CODE. Specific points discussed included age-year cut-off, threshold of each tool/item and information about social support, but no additional item was proposed. CONCLUSION: We achieved formal consensus on a set of geriatric data to be collected in cancer trials of older patients. The dissemination and prospective use of the G-CODE is needed to assess its utility. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | CIC1401 | |
| dc.subject.en | EPICENE | |
| dc.title.en | Multidisciplinary development of the Geriatric Core Dataset for clinical research in older patients with cancer: A French initiative with international survey | |
| dc.title.alternative | Eur J Cancer | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.ejca.2018.07.137 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 30212804 | en_US |
| bordeaux.journal | European journal of cancer | en_US |
| bordeaux.page | 61-68 | en_US |
| bordeaux.volume | 103 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.team | CIC1401 | en_US |
| bordeaux.team | EPICENE_BPH | |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-03194137 | |
| hal.version | 1 | |
| hal.date.transferred | 2021-04-09T11:00:32Z | |
| hal.export | true | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=European%20journal%20of%20cancer&rft.date=2018-11&rft.volume=103&rft.spage=61-68&rft.epage=61-68&rft.eissn=1879-0852%20(Electronic)%200959-8049%20(Linking)&rft.issn=1879-0852%20(Electronic)%200959-8049%20(Linking)&rft.au=PAILLAUD,%20E.&SOUBEYRAN,%20P.&CAILLET,%20P.&CUDENNEC,%20T.&BRAIN,%20E.&rft.genre=article |
Files in this item
| Files | Size | Format | View |
|---|---|---|---|
|
There are no files associated with this item. |
|||