Mini-fluid Challenge of 100 ml of Crystalloid Predicts Fluid Responsiveness in the Operating Room.
| dc.rights.license | open | en_US |
| hal.structure.identifier | Biologie des maladies cardiovasculaires = Biology of Cardiovascular Diseases | |
| dc.contributor.author | BIAIS, M. | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | DE COURSON DE LA VILLENEUVE, Hugues | |
| dc.contributor.author | LANCHON, R. | |
| dc.contributor.author | PEREIRA, B. | |
| dc.contributor.author | BARDONNEAU, G. | |
| dc.contributor.author | GRITON, M. | |
| dc.contributor.author | SESAY, M. | |
| dc.contributor.author | NOUETTE-GAULAIN, Karine | |
| dc.date.accessioned | 2020 | |
| dc.date.available | 2020 | |
| dc.date.issued | 2017 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/20893 | |
| dc.description.abstractEn | BACKGROUND: Mini-fluid challenge of 100 ml colloids is thought to predict the effects of larger amounts of fluid (500 ml) in intensive care units. This study sought to determine whether a low quantity of crystalloid (50 and 100 ml) could predict the effects of 250 ml crystalloid in mechanically ventilated patients in the operating room. METHODS: A total of 44 mechanically ventilated patients undergoing neurosurgery were included. Volume expansion (250 ml saline 0.9%) was given to maximize cardiac output during surgery. Stroke volume index (monitored using pulse contour analysis) and pulse pressure variations were recorded before and after 50 ml infusion (given for 1 min), after another 50 ml infusion (given for 1 min), and finally after 150 ml infusion (total = 250 ml). Changes in stroke volume index induced by 50, 100, and 250 ml were recorded. Positive fluid challenges were defined as an increase in stroke volume index of 10% or more from baseline after 250 ml. RESULTS: A total of 88 fluid challenges were performed (32% of positive fluid challenges). Changes in stroke volume index induced by 100 ml greater than 6% (gray zone between 4 and 7%, including 19% of patients) predicted fluid responsiveness with a sensitivity of 93% (95% CI, 77 to 99%) and a specificity of 85% (95% CI, 73 to 93%). The area under the receiver operating curve of changes in stroke volume index induced by 100 ml was 0.95 (95% CI, 0.90 to 0.99) and was higher than those of changes in stroke volume index induced by 50 ml (0.83 [95% CI, 0.75 to 0.92]; P = 0.01) and pulse pressure variations (0.65 [95% CI, 0.53 to 0.78]; P \textless 0.005). CONCLUSIONS: Changes in stroke volume index induced by rapid infusion of 100 ml crystalloid predicted the effects of 250 ml crystalloid in patients ventilated mechanically in the operating room. | |
| dc.language.iso | EN | en_US |
| dc.subject | *Article CLINIQUE | |
| dc.title.en | Mini-fluid Challenge of 100 ml of Crystalloid Predicts Fluid Responsiveness in the Operating Room. | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1097/ALN.0000000000001753 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Médecine humaine et pathologie | en_US |
| bordeaux.journal | Anesthesiology | en_US |
| bordeaux.page | 450–456 | en_US |
| bordeaux.volume | 127 | en_US |
| bordeaux.hal.laboratories | Biologie des maladies cardiovasculaires - U1034 | en_US |
| bordeaux.issue | 3 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | |
| bordeaux.team | BIOSTAT_BPH | |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.export | false | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Anesthesiology&rft.date=2017&rft.volume=127&rft.issue=3&rft.spage=450%E2%80%93456&rft.epage=450%E2%80%93456&rft.au=BIAIS,%20M.&DE%20COURSON%20DE%20LA%20VILLENEUVE,%20Hugues&LANCHON,%20R.&PEREIRA,%20B.&BARDONNEAU,%20G.&rft.genre=article |
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