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Efficacy of advancement treatments of the stomatognathic system on objective sleepiness in OSA: a systematic review

dc.rights.licenseopenen_US
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
dc.contributor.authorGALVEZ, Paul
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
hal.structure.identifierCentre Hospitalier Universitaire de Bordeaux [CHU Bordeaux]
dc.contributor.authorD’INCAU, Emmanuel
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
dc.contributor.authorTAILLARD, Jacques
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
hal.structure.identifierLaboratoire Bordelais de Recherche en Informatique [LaBRI]
dc.contributor.authorP. MARTIN, Vincent
hal.structure.identifierCentre for Research in Epidemiology and Statistics | Centre de Recherche Épidémiologie et Statistiques [CRESS (U1153 / UMR_A 1125)]
hal.structure.identifierCHU Rothschild [AP-HP]
dc.contributor.authorCARRA, Maria Clotilde
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
hal.structure.identifierCentre Hospitalier Universitaire de Bordeaux [CHU Bordeaux]
dc.contributor.authorFENELON, Mathilde
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorCHUY, Virginie
IDREF: 234159758
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
dc.contributor.authorCOELHO, Julien
hal.structure.identifierSommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY]
dc.contributor.authorPHILIP, Pierre
hal.structure.identifierCentre Hospitalier Universitaire de Bordeaux [CHU Bordeaux]
hal.structure.identifierCentre National de la Recherche Scientifique [CNRS]
dc.contributor.authorMICOULAUD-FRANCHI, Jean-Arthur
dc.date.accessioned2025-05-22T14:08:59Z
dc.date.available2025-05-22T14:08:59Z
dc.date.issued2025-04-22
dc.identifier.issn1550-9389en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/206679
dc.description.abstractEnSTUDY OBJECTIVES: Objective sleepiness is an important outcome requiring rigorous evaluation regarding OSA treatment efficacy, but no systematic review has explored the efficacy of advancement treatments of the stomatognathic system (ATSS), i.e. mandibular advancement device (MAD), hypoglossal nerve stimulation (HNS), and maxillomandibular advancement surgery (MMA), on objective sleepiness in OSA. METHODS: We conducted a systematic review of the literature using PubMed, Scopus and Web of Science databases. All clinical studies assessing the efficacy of ATSS on objective sleepiness in adults with OSA, by the maintenance of wakefulness test (MWT), the multiple sleep latency test (MSLT), the Oxford sleep resistance test (OSLER), the psychomotor vigilance task (PVT) or the sustained attention to response task (SART), were included. RESULTS: Among 42 screened studies, 11 were included - 6 randomized controlled trials (RCTs) and 5 prospective studies. Regarding the RCTs, all assessed MAD efficacy and only one RCT found a significant improvement of objective sleepiness for MAD compared with placebo, on the MSLT. In the remaining RCTs, the included participants did not present objective sleepiness at baseline and were mostly with mild/moderate OSA. Regarding the prospective studies, all found a significant improvement of objective sleepiness for each treatment assessed, i.e. MAD, HNS, MMA and submental stimulation. Interestingly, the included participants presented objective sleepiness at baseline and moderate/severe OSA. CONCLUSIONS: This systematic review highlighted the lack of RCTs assessing the efficacy of MAD or other ATSS on objective sleepiness in OSA. Further RCTs are needed to address this important outcome taking into account baseline objective sleepiness and OSA severity.
dc.language.isoENen_US
dc.subject.enAlertness
dc.subject.enExcessive Daytime Sleepiness
dc.subject.enHypoglossal Nerve Stimulation
dc.subject.enMaintenance Of Wakefulness Test
dc.subject.enMandibular Advancement Device
dc.subject.enMaxillomandibular Advancement
dc.subject.enObjective Sleepiness
dc.subject.enObstructive Sleep Apnea
dc.title.enEfficacy of advancement treatments of the stomatognathic system on objective sleepiness in OSA: a systematic review
dc.title.alternativeJ Clin Sleep Meden_US
dc.typeArticle de revueen_US
dc.identifier.doi10.5664/jcsm.11730en_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologieen_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologie/Physiologie [q-bio.TO]en_US
dc.identifier.pubmed40259747en_US
bordeaux.journalJournal of Clinical Sleep Medicineen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCNRS
bordeaux.institutionCHU de Bordeaux
bordeaux.institutionInstitut Bergonié
bordeaux.institutionBordeaux INP
bordeaux.teamLEHA_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-05051864
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccPas de Licence CCen_US
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