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Psychoactive cocktail consumption on Reunion Island: A case report

dc.rights.licenseopenen_US
dc.contributor.authorGUYON, Joris
dc.contributor.authorMAILLOT, Adrien
dc.contributor.authorBASTARD, Sophie
dc.contributor.authorWEISSE, Flore
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDAVELUY, Amelie
ORCID: 0000-0003-1922-8630
IDREF: 07603934X
dc.contributor.authorMETE, David
dc.date.accessioned2025-04-11T06:36:46Z
dc.date.available2025-04-11T06:36:46Z
dc.date.issued2025-02-15
dc.identifier.issn1945-2403en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/206112
dc.description.abstractEnReunion Island is a French department located in the southwestern Indian Ocean, with distinct trends in drug use, drug diversion and intoxication compared with metropolitan France (e.g. the misuse of drugs - clonazepam and trihexyphenidyl - combined with cannabis or cocaine, which is not observed in metropolitan France). The authors report a case of atypical intoxication in a 16-year-old female who consumed cannabis in conjunction with an unusual powdered mixture containing psychotropic substances. The intoxication led to confusion, hallucinations, sinus tachycardia and hospitalization. A comprehensive high-resolution mass spectrometry and liquid-chromatography mass spectrometry analysis of her plasma, her urine and a powder found in her possession revealed the presence of the same 5 medicines: citalopram/escitalopram, paroxetine, sertraline, venlafaxine and trihexyphenidyl. This case underscores the intricate interactions between psychoactive substances that are never prescribed together in clinical settings, along with the issue of diverted prescription drugs like trihexyphenidyl. It also emphasizes the potential circulation and use of crushed mixtures of medication for recreational purpose. Fortunately, powder analysis provided crucial insight to understand the intoxication.
dc.language.isoENen_US
dc.subject.enAntidepressant
dc.subject.enDrug Misuse
dc.subject.enIntoxication
dc.subject.enTeenager
dc.subject.enTrihexyphenidyl
dc.title.enPsychoactive cocktail consumption on Reunion Island: A case report
dc.title.alternativeJ Anal Toxicolen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1093/jat/bkaf009en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed39953779en_US
bordeaux.journalJournal of Analytical Toxicologyen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamAHEAD_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-05030177
hal.version1
hal.date.transferred2025-04-11T06:36:49Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20Analytical%20Toxicology&rft.date=2025-02-15&rft.eissn=1945-2403&rft.issn=1945-2403&rft.au=GUYON,%20Joris&MAILLOT,%20Adrien&BASTARD,%20Sophie&WEISSE,%20Flore&DAVELUY,%20Amelie&rft.genre=article


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