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Arteriovenous access creation and hazards of hospitalization and death in patients starting hemodialysis

dc.rights.licenseopenen_US
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorDE PINHO, Natalia Alencar
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorPREZELIN-REYDIT, Mathilde
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorHARAMBAT, Jerome
dc.contributor.authorCOUCHOUD, Cécile
dc.contributor.authorGLAUDET, Florence
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorCOMBE, Christian
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorRONDEAU, Virginie
ORCID: 0000-0001-7109-4831
IDREF: 16662988X
hal.structure.identifierBordeaux population health [BPH]
dc.contributor.authorLEFFONDRÉ, Karen
dc.date.accessioned2025-03-27T15:30:42Z
dc.date.available2025-03-27T15:30:42Z
dc.date.issued2024-05-31
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/205730
dc.description.abstractEnBackground: Recent evidence suggests an overestimation of the benefits associated with arteriovenous (AV) fistula versus graft in certain populations. We assessed hazards of all-cause and cause-specific hospitalization and death associated with AV access type in patients who started hemodialysis with a catheter in France, overall and by subgroups of age, sex and comorbidities. Methods: We performed a target trial emulation including patients who initiated hemodialysis with a catheter from 2010 through 2018 and were followed by the REIN Registry. We identified first-created fistula or graft through the French national health-administrative database. We used joint frailty models to deal with recurrent hospitalizations and potential informative censoring by death, and inverse probability weighting to account for confounding. Results: From the 18 800 patients included (mean age 68 ± 15 years, 35% women), 5% underwent AV graft creation first. The weighted hazard ratio (wHR) of all-cause hospitalization associated with graft was 1.08 [95% confidence interval (CI) 1.02 to 1.15], that of vascular access-related hospitalization was 1.43 (95% CI 1.32 to 1.55), and those of cardiovascular- and infection-related hospitalizations were 1.14 (95% CI 1.03 to 1.26) and 1.11 (95% CI 0.97 to 1.28), respectively. Results were consistent for most subgroups, except that the highest hazard of all-cause, cardiovascular- and infection-related hospitalizations with graft was blunted in patients with comorbidities (i.e. diabetes, wHR 1.01, 95% CI 0.93 to 1.10; 1.10, 95% CI 0.96 to 1.26; and 0.94, 95% CI 0.78 to 1.12, respectively). Conclusions: In patients starting hemodialysis with a catheter, AV graft creation is associated with increased hazard of vascular access-related hospitalizations compared with fistula. This may not be the case for death or other causes of hospitalization. © 2023 The Author(s). Published by Oxford University Press on behalf of the ERA.
dc.language.isoENen_US
dc.subjectarteriovenous fistula
dc.subjectarteriovenous graft
dc.subjecthospitalization
dc.subjectoutcomes
dc.subjectvascular access
dc.title.enArteriovenous access creation and hazards of hospitalization and death in patients starting hemodialysis
dc.typeArticle de revueen_US
dc.identifier.doi10.1093/ndt/gfad251en_US
dc.subject.halSciences du Vivant [q-bio]en_US
bordeaux.journalNephrology Dialysis Transplantationen_US
bordeaux.page978 – 988en_US
bordeaux.volume39en_US
bordeaux.hal.laboratoriesBioingénierie Tissulaire (BioTis) - U1026en_US
bordeaux.issue6en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCHU de Bordeauxen_US
bordeaux.institutionInstitut Bergoniéen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nephrology%20Dialysis%20Transplantation&rft.date=2024-05-31&rft.volume=39&rft.issue=6&rft.spage=978%20%E2%80%93%20988&rft.epage=978%20%E2%80%93%20988&rft.au=DE%20PINHO,%20Natalia%20Alencar&PREZELIN-REYDIT,%20Mathilde&HARAMBAT,%20Jerome&COUCHOUD,%20C%C3%A9cile&GLAUDET,%20Florence&rft.genre=article


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