The serotonin2B receptor and neurochemical regulation in the brain
| dc.rights.license | open | en_US |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | SPAMPINATO, Umberto | |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | CATHALA, Adeline | |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | DEVROYE, Celine | |
| dc.contributor.editor | CUNNINGHAM, Kathryn A. | |
| dc.contributor.editor | MULLER, Christian P. | |
| dc.date.accessioned | 2025-03-20T15:51:01Z | |
| dc.date.available | 2025-03-20T15:51:01Z | |
| dc.date.issued | 2020 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/205590 | |
| dc.description.abstractEn | The serotonin2B receptor (5-HT2BR) is the most recent addition to the 5-HT2R family. During the last decade, a growing number of studies have shown that the central 5-HT2BR participates in the control of dopamine (DA) and serotonin (5-HT) neuron activity, thereby highlighting its key role for future therapeutic strategies of DA-related neuropsychiatric disorders. This chapter, after a reminder of the 5-HT2BR expression in the central nervous system and the 5-HT2BR agonists and antagonists available today, will focus on the role of this receptor in the control of 5-HT and DA activity in the rodent brain, by encompassing electrophysiological and neurochemical data issued from in vitro and in vivo studies. This overview will provide a functional basis to understand the therapeutic relevance of this receptor for treating DA-dependent neuropsychiatric disorders such as schizophrenia and drug addiction. © 2020 Elsevier B.V. | |
| dc.language.iso | EN | en_US |
| dc.publisher | Elsevier | en_US |
| dc.source.title | Handbook of the Behavioral Neurobiology of Serotonin | en_US |
| dc.subject.en | Serotonin 2b Receptor | |
| dc.subject.en | Binding Affinity | |
| dc.subject.en | Brain | |
| dc.subject.en | Central Nervous System | |
| dc.subject.en | Dorsal Raphe Nucleus | |
| dc.subject.en | Drug Dependence | |
| dc.subject.en | Human | |
| dc.subject.en | Interneuron | |
| dc.subject.en | Medial Prefrontal Cortex | |
| dc.subject.en | Mental Disease | |
| dc.subject.en | Nerve Cell | |
| dc.subject.en | Neurochemistry | |
| dc.subject.en | Neuropharmacology | |
| dc.subject.en | Nonhuman | |
| dc.subject.en | Pyramidal Nerve Cell | |
| dc.subject.en | Schizophrenia | |
| dc.subject.en | Ventral Tegmentum | |
| dc.title.en | The serotonin2B receptor and neurochemical regulation in the brain | |
| dc.type | Chapitre d'ouvrage | en_US |
| dc.identifier.doi | 10.1016/B978-0-444-64125-0.00007-4 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC] | en_US |
| bordeaux.page | 147-156 | en_US |
| bordeaux.volume | 31 | en_US |
| bordeaux.hal.laboratories | Neurocentre Magendie - U1215 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-04999275 | |
| hal.version | 1 | |
| hal.date.transferred | 2025-03-20T15:51:04Z | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.btitle=Handbook%20of%20the%20Behavioral%20Neurobiology%20of%20Serotonin&rft.date=2020&rft.volume=31&rft.spage=147-156&rft.epage=147-156&rft.au=SPAMPINATO,%20Umberto&CATHALA,%20Adeline&DEVROYE,%20Celine&rft.genre=unknown |
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