Isopentenyl diphosphate isomerase: A checkpoint to isoprenoid biosynthesis
| dc.rights.license | open | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| dc.contributor.author | BERTHELOT, Karine | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| dc.contributor.author | ESTEVEZ, Yannick | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| dc.contributor.author | DEFFIEUX, Alain | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 1 LCPO : Polymerization Catalyses & Engineering | |
| dc.contributor.author | PERUCH, Frédéric
IDREF: 152900748 | |
| dc.date.accessioned | 2020 | |
| dc.date.available | 2020 | |
| dc.date.issued | 2012 | |
| dc.identifier.issn | 0300-9084 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/20491 | |
| dc.description.abstractEn | Even if the isopentenyl diphosphate (IPP) isomerases have been discovered in the 50s, it is only in the last decade that the genetical, enzymatical, structural richness and cellular importance of this large family of crucial enzymes has been uncovered. Present in all living kingdoms, they can be classified in two subfamilies: type 1 and type 2 IPP isomerases, which show clearly distinct characteristics. They all perform the regulatory isomerization of isopentenyl diphosphate into dimethylallyl diphosphate, a key rate-limiting step of the terpenoid biosynthesis, via a protonation/deprotonation mechanism. Due to their importance in the isoprenoid metabolism and the increasing interest of industry devoted to terpenoid production, it is foreseen that the biotechnological development of such enzymes should be under intense scrutiny in the near future. | |
| dc.language.iso | en | |
| dc.publisher | Elsevier | |
| dc.subject.en | Terpens | |
| dc.subject.en | Isoprenoid synthesis | |
| dc.subject.en | Isopentenyl diphosphate isomerase | |
| dc.subject.en | IPP | |
| dc.subject.en | DMAPP | |
| dc.title.en | Isopentenyl diphosphate isomerase: A checkpoint to isoprenoid biosynthesis | |
| dc.type | Article de revue | |
| dc.identifier.doi | 10.1016/j.biochi.2012.03.021 | |
| dc.subject.hal | Chimie/Polymères | |
| bordeaux.journal | Biochimie | |
| bordeaux.page | 1621-1634 | |
| bordeaux.volume | 94 | |
| bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
| bordeaux.issue | 8 | |
| bordeaux.institution | Bordeaux INP | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.peerReviewed | oui | |
| hal.identifier | hal-00744301 | |
| hal.version | 1 | |
| hal.origin.link | https://hal.archives-ouvertes.fr//hal-00744301v1 | |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Biochimie&rft.date=2012&rft.volume=94&rft.issue=8&rft.spage=1621-1634&rft.epage=1621-1634&rft.eissn=0300-9084&rft.issn=0300-9084&rft.au=BERTHELOT,%20Karine&ESTEVEZ,%20Yannick&DEFFIEUX,%20Alain&PERUCH,%20Fr%C3%A9d%C3%A9ric&rft.genre=article |
Fichier(s) constituant ce document
| Fichiers | Taille | Format | Vue |
|---|---|---|---|
|
Il n'y a pas de fichiers associés à ce document. |
|||