Systematic Aetiological Assessment of Myocarditis: A Prospective Cohort Study
| dc.rights.license | open | en_US |
| dc.contributor.author | MICHEL, Vincent | |
| dc.contributor.author | LAZARO, Estibaliz | |
| dc.contributor.author | FAUTHOUX, Thomas | |
| dc.contributor.author | CETRAN, Laura | |
| hal.structure.identifier | Immunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle [ImmunoConcept] | |
| dc.contributor.author | CONTIN-BORDES, Cécile | |
| hal.structure.identifier | Immunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle [ImmunoConcept] | |
| dc.contributor.author | BLANCO, Patrick | |
| dc.contributor.author | SEGUY, Benjamin | |
| dc.contributor.author | BAUDINET, Thomas | |
| dc.contributor.author | COSTE, Pierre | |
| dc.contributor.author | GERBAUD, Edouard | |
| dc.date.accessioned | 2025-02-10T15:08:00Z | |
| dc.date.available | 2025-02-10T15:08:00Z | |
| dc.date.issued | 2024-02 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/204783 | |
| dc.description.abstractEn | Myocarditis is commonly diagnosed in the intensive care cardiology unit (ICCU). No current recommendation nor guideline aids exist for aetiological assessments. Methods: From September 2021 to October 2023, 84 patients with acute myocarditis underwent thorough and systematic serum and blood cell panel evaluations to determine the most common causes of myocarditis. Results: Of the 84 patients (median age 34 years, range 22–41 years, 79% male), 16 presented with complicated myocarditis. The systematic aetiological assessment revealed that 36% of patients were positive for lupus anticoagulant, 12% for antinuclear antibodies, 8% for anti-heart antibodies, and 12% for anti-striated muscle antibodies. Viral serology did not yield any significant results. After the aetiological assessment, one patient was diagnosed with an autoimmune inflammatory disorder (Still’s disease). T-cell subset analyses indicated that myocarditis severity tended to increase with the T-cell lymphopenia status. Conclusions: A comprehensive, systematic aetiological assessment was of limited value in terms of predicting the clinical or therapeutic outcomes in myocarditis patients presenting to the ICCU. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.subject.en | Myocarditis | |
| dc.subject.en | Autoimmune and inflammatory disorders | |
| dc.subject.en | Aetiological assessment | |
| dc.title.en | Systematic Aetiological Assessment of Myocarditis: A Prospective Cohort Study | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.3390/jcm13041025 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Immunologie | en_US |
| dc.identifier.pubmed | 38398340 | en_US |
| bordeaux.journal | Journal of Clinical Medicine | en_US |
| bordeaux.volume | 13 | en_US |
| bordeaux.hal.laboratories | ImmunoConcEpT - UMR 5164 | en_US |
| bordeaux.issue | 4 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-04938801 | |
| hal.version | 1 | |
| hal.date.transferred | 2025-02-10T15:08:03Z | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | true | |
| dc.rights.cc | CC BY | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20Clinical%20Medicine&rft.date=2024-02&rft.volume=13&rft.issue=4&rft.au=MICHEL,%20Vincent&LAZARO,%20Estibaliz&FAUTHOUX,%20Thomas&CETRAN,%20Laura&CONTIN-BORDES,%20C%C3%A9cile&rft.genre=article |