Biofunctional micellar nanoparticles from peptide-b-polymer chimeras
dc.rights.license | open | |
hal.structure.identifier | Institut Européen de Chimie et de Biologie [IECB] | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
dc.contributor.author | DRAPPIER, Charlotte | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
dc.contributor.author | WIROTIUS, Anne-Laure | |
hal.structure.identifier | Chimie et Biologie des Membranes et des Nanoobjets [CBMN] | |
dc.contributor.author | BATHANY, Katell | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
dc.contributor.author | IBARBOURE, Emmanuel | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
dc.contributor.author | CONDASSAMY, Olivia | |
hal.structure.identifier | Institut Européen de Chimie et de Biologie [IECB] | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
dc.contributor.author | GARANGER, Elisabeth
IDREF: 089451740 | |
hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
dc.contributor.author | LECOMMANDOUX, Sebastien | |
dc.date.accessioned | 2020 | |
dc.date.available | 2020 | |
dc.date.issued | 2013 | |
dc.identifier.issn | 1759-9954 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/20411 | |
dc.description.abstractEn | We describe the precision synthesis and characterization of amphiphilic peptide-b-polymer chimeras encoding, at the molecular level, self-assembly properties and biological functions, presently cell membrane penetrating motifs (Tat peptide). Self-assembled micellar nanoparticles obtained from a series of Tat-b-poly(trimethylene carbonate) (Tat-b-PTMC) chimeras with tunable hydrophilic fractions were finely characterized in order to establish chimera-nanoparticle structure relationships. Well-defined nanoparticles with diameters ranging from 22 to 40 nm could be obtained by direct self-assembly in buffer. | |
dc.language.iso | en | |
dc.publisher | Royal Society of Chemistry - RSC | |
dc.subject.en | HIV-1 | |
dc.subject.en | SIRNA | |
dc.subject.en | MEMBRANE | |
dc.subject.en | PROTEIN | |
dc.subject.en | INTRACELLULAR DRUG-DELIVERY | |
dc.subject.en | CELL-PENETRATING PEPTIDES | |
dc.subject.en | SYNTHETIC-POLYMER | |
dc.subject.en | BLOCK-COPOLYMERS | |
dc.subject.en | TAT PEPTIDE | |
dc.subject.en | SPECTROSCOPY | |
dc.title.en | Biofunctional micellar nanoparticles from peptide-b-polymer chimeras | |
dc.type | Article de revue | |
dc.identifier.doi | 10.1039/c2py21044d | |
dc.subject.hal | Chimie/Polymères | |
bordeaux.journal | Polymer Chemistry | |
bordeaux.page | 2011-2018 | |
bordeaux.volume | 4 | |
bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | * |
bordeaux.issue | 6 | |
bordeaux.institution | Bordeaux INP | |
bordeaux.institution | Université de Bordeaux | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-00846289 | |
hal.version | 1 | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-00846289v1 | |
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