Pleural mesothelioma and occupational coexposure to asbestos, mineral wool, and silica
| dc.rights.license | open | en_US |
| hal.structure.identifier | INSERM, Equipe PPCT, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique | |
| dc.contributor.author | LACOURT, Aude | |
| hal.structure.identifier | INSERM, Equipe PPCT, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique | |
| dc.contributor.author | GRAMOND, Celine | |
| hal.structure.identifier | INSERM, Equipe PPCT, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique | |
| dc.contributor.author | AUDIGNON, Sabyne
ORCID: 0000-0002-5056-1397 IDREF: 134088123 | |
| dc.contributor.author | DUCAMP, Stéphane | |
| dc.contributor.author | FÉVOTTE, Joelle | |
| dc.contributor.author | SOIT ILG, Annabelle Gilg | |
| dc.contributor.author | GOLDBERG, Marcel | |
| dc.contributor.author | IMBERNON, Ellen | |
| hal.structure.identifier | INSERM, Equipe PPCT, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique | |
| dc.contributor.author | BROCHARD, Patrick
ORCID: 0000-0002-5056-1397 IDREF: 134088123 | |
| dc.date.accessioned | 2024-12-04T09:37:14Z | |
| dc.date.available | 2024-12-04T09:37:14Z | |
| dc.date.issued | 2013-05-01 | |
| dc.identifier.issn | 1535-4970 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/203685 | |
| dc.description.abstractEn | Occupational coexposure to asbestos and other fibers or particles could modify the carcinogenicity of asbestos with regard to pleural mesothelioma. To estimate associations between pleural mesothelioma and occupational mineral wool and silica exposure and to study the impact of occupational coexposure on the risk of pleural mesothelioma. A total of 1,199 male cases and 2,379 control subjects were included in a French pooled case-control study. Complete job histories were collected, and occupational exposure to asbestos, mineral wool (MW), and silica were assessed by three French job exposure matrices. Unconditional logistic regression models adjusted for age, birth date, and occupational asbestos exposure were used to estimate odds ratios (OR) and 95% confidence intervals (CIs). A significant association between mesothelioma and MW exposure was observed after adjustment for occupational asbestos exposure. OR for subjects exposed to less than 0.01 fibers·ml(-1)·yr(-1) was 1.6 (95% CI, 1.2-2.1) and increased to 2.5 (95% CI, 1.8-3.4) for subjects exposed to more than 0.32 fibers·ml(-1)·yr(-1). All ORs for silica exposure were around the null. Coexposure to either asbestos and MW or asbestos and silica seemed to increase the risk of pleural mesothelioma. ORs were 17.6 (95% CI, 11.8-26.2) and 9.8 (95% CI, 4.2-23.2) for subjects exposed to both asbestos and MW and for subjects exposed to both asbestos and silica, respectively, compared with 4.3 (95% CI, 1.9-9.8) for occupational asbestos exposure alone. Our results are in favor of an increased risk of pleural mesothelioma for subjects exposed to both asbestos and MW or asbestos and silica. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Aged | |
| dc.subject.en | Asbestos | |
| dc.subject.en | Calcium Compounds | |
| dc.subject.en | Case-Control Studies | |
| dc.subject.en | France | |
| dc.subject.en | Humans | |
| dc.subject.en | Logistic Models | |
| dc.subject.en | Male | |
| dc.subject.en | Mesothelioma | |
| dc.subject.en | Middle Aged | |
| dc.subject.en | Occupational Diseases | |
| dc.subject.en | Occupational Exposure | |
| dc.subject.en | Odds Ratio | |
| dc.subject.en | Pleural Neoplasms | |
| dc.subject.en | Risk | |
| dc.subject.en | Silicates | |
| dc.subject.en | Silicon Dioxide | |
| dc.title.en | Pleural mesothelioma and occupational coexposure to asbestos, mineral wool, and silica | |
| dc.title.alternative | Am J Respir Crit Care Med | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1164/rccm.201210-1911OC | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 23471464 | en_US |
| bordeaux.journal | American Journal of Respiratory and Critical Care Medicine | en_US |
| bordeaux.page | 977-982 | en_US |
| bordeaux.volume | 187 | en_US |
| bordeaux.hal.laboratories | Anciens laboratoires de l'Université de Bordeaux | en_US |
| bordeaux.issue | 9 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | pubmed | |
| hal.identifier | hal-04818212 | |
| hal.version | 1 | |
| hal.date.transferred | 2024-12-04T09:37:16Z | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | true | |
| workflow.import.source | pubmed | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=American%20Journal%20of%20Respiratory%20and%20Critical%20Care%20Medicine&rft.date=2013-05-01&rft.volume=187&rft.issue=9&rft.spage=977-982&rft.epage=977-982&rft.eissn=1535-4970&rft.issn=1535-4970&rft.au=LACOURT,%20Aude&GRAMOND,%20Celine&AUDIGNON,%20Sabyne&DUCAMP,%20St%C3%A9phane&F%C3%89VOTTE,%20Joelle&rft.genre=article |
Fichier(s) constituant ce document
| Fichiers | Taille | Format | Vue |
|---|---|---|---|
|
Il n'y a pas de fichiers associés à ce document. |
|||