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Prevalence and co-occurrence of symptoms of mental and substance use disorders among people with HIV age 40 and older in low- and middle-income countries: a cross-sectional study.

dc.rights.licenseopenen_US
dc.contributor.authorPARCESEPE, Angela M
dc.contributor.authorSTOCKTON, Melissa
hal.structure.identifierBordeaux population health [BPH]
hal.structure.identifierGlobal Health in the Global South [GHiGS]
dc.contributor.authorBERNARD, Charlotte
ORCID: 0000-0003-2677-4023
dc.contributor.authorKANGUYA, Tukiya
dc.contributor.authorKWOBAH, Edith Kamaru
dc.contributor.authorLOPEZ, Alvaro
dc.contributor.authorMURENZI, Gad
dc.contributor.authorROSS, Jeremy
dc.contributor.authorMINGA, Albert
dc.contributor.authorMARURI, Fernanda
dc.contributor.authorTLALI, Mpho
dc.contributor.authorGOODRICH, Suzanne
dc.contributor.authorPERAZZO, Hugo
dc.contributor.authorMUSABYIMANA, Françoise
dc.contributor.authorNIMKAR, Smita
dc.contributor.authorLANCASTER, Kathryn
dc.contributor.authorCONSORTIUM, IeDEA
dc.date.accessioned2024-11-28T14:48:04Z
dc.date.available2024-11-28T14:48:04Z
dc.date.issued2024-10-01
dc.identifier.issn1758-2652en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/203522
dc.description.abstractEnDue to the increased effectiveness of and access to antiretroviral therapy (ART), people with HIV (PWH) are living longer. As a result, the population of older PWH has increased. Mental and substance use disorders (MSDs) are common and frequently co-occurring among PWH and are associated with poor HIV care outcomes. Research into the prevalence and co-occurrence of MSDs among ageing PWH remains limited, particularly in low- and middle-income countries (LMICs). We analysed data collected between 2020 and 2022 from the International epidemiology Databases to Evaluate AIDS (IeDEA) Sentinel Research Network cohort of PWH aged 40 years or older on ART at 11 HIV clinics in Brazil, Côte d'Ivoire, India, Kenya, Mexico, Uganda, Rwanda, Togo, Vietnam, Zambia and Zimbabwe. We estimated the prevalence and co-occurrence of unhealthy alcohol use (AUDIT-C ≥3 for women, ≥4 for men), unhealthy drug use (ASSIST >3 for cannabis, cocaine, amphetamines, inhalants, sedatives, hallucinogens and/or opioids), and moderate to severe symptoms of depression (PHQ-9 ≥10), anxiety (GAD-7 ≥10) and post-traumatic stress disorder (PTSD) (PCL-5 ≥33). Psychiatric multimorbidity was defined as having symptoms of two or more disorders assessed. Log binomial models assessed the association between socio-demographic and HIV care characteristics and symptoms of anxiety, depression, PTSD or unhealthy substance use. Of 2821 participants, the prevalence of unhealthy alcohol and drug use was 21% and 5%, respectively. The prevalence of moderate to severe symptoms of depression, anxiety and PTSD was 14%, 9% and 6%, respectively. Overall, the prevalence of psychiatric multimorbidity was 11%. Among those with symptoms of at least one mental health or substance use outcome assessed (n = 1036), the prevalence of psychiatric multimorbidity was 31%. In binomial models, the prevalence of symptoms of depression and anxiety was higher, while the prevalence of unhealthy alcohol and drug use was lower among women than men. Unhealthy alcohol use and symptoms of depression were most commonly reported, among this cohort of PWH aged 40 or older across 11 LMICs. Integration of MSD screening and treatment into HIV care should be prioritized. The effectiveness and implementation of transdiagnostic or multi-focus mental health treatment approaches in HIV care settings should be examined.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enHumans
dc.subject.enFemale
dc.subject.enMale
dc.subject.enPrevalence
dc.subject.enCross-Sectional Studies
dc.subject.enSubstance-Related Disorders
dc.subject.enHIV Infections
dc.subject.enAdult
dc.subject.enMiddle Aged
dc.subject.enMental Disorders
dc.subject.enDeveloping Countries
dc.subject.enAged
dc.subject.enComorbidity
dc.title.enPrevalence and co-occurrence of symptoms of mental and substance use disorders among people with HIV age 40 and older in low- and middle-income countries: a cross-sectional study.
dc.title.alternativeJ Int AIDS Socen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1002/jia2.26359en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed39375051en_US
bordeaux.journalJournal of the International AIDS Societyen_US
bordeaux.pagee26359en_US
bordeaux.volume27en_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.issue10en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamGHIGS_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDInstitut de Recherche pour le Développementen_US
bordeaux.identifier.funderIDNational Institute of Allergy and Infectious Diseasesen_US
bordeaux.identifier.funderIDNational Institute on Drug Abuseen_US
bordeaux.identifier.funderIDNational Institute of Mental Healthen_US
bordeaux.identifier.funderIDFogarty International Centeren_US
bordeaux.import.sourcepubmed
hal.identifierhal-04809397
hal.version1
hal.date.transferred2024-11-28T14:48:08Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcepubmed
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20the%20International%20AIDS%20Society&rft.date=2024-10-01&rft.volume=27&rft.issue=10&rft.spage=e26359&rft.epage=e26359&rft.eissn=1758-2652&rft.issn=1758-2652&rft.au=PARCESEPE,%20Angela%20M&STOCKTON,%20Melissa&BERNARD,%20Charlotte&KANGUYA,%20Tukiya&KWOBAH,%20Edith%20Kamaru&rft.genre=article


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