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The conundrum of the complex relationship between acute kidney injury and cardiac arrhythmias

dc.rights.licenseopenen_US
dc.contributor.authorGENOVESI, S.
dc.contributor.authorREGOLISTI, G.
dc.contributor.authorBURLACU, A.
dc.contributor.authorCOVIC, A.
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorCOMBE, C.
dc.contributor.authorMITRA, S.
dc.contributor.authorBASILE, C.
dc.contributor.authorERA, EuDialWorking Group Of
dc.date.accessioned2024-10-25T09:41:45Z
dc.date.available2024-10-25T09:41:45Z
dc.date.issued2023
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/202806
dc.description.abstractEnAcute kidney injury (AKI) is defined by a rapid increase in serum creatinine levels, reduced urine output or both. Death may occur in 16-49% of patients admitted to an intensive care unit with severe AKI. Complex arrhythmias are a potentially serious complication in AKI patients with pre-existing or AKI-induced heart damage and myocardial dysfunction, with fluid overload, especially electrolyte and acid-base disorders, representing the pathogenetic mechanisms of arrhythmogenesis. Cardiac arrhythmias, in turn, increase the risk of poor renal outcomes, including AKI. Arrhythmic risk in AKI patients receiving kidney replacement treatment may be reduced by modifying dialysis/replacement fluid composition. The most common arrhythmia observed in AKI patients is atrial fibrillation. Severe hyperkalaemia, sometimes combined with hypocalcaemia, causes severe bradyarrhythmias in this clinical setting. Although the likelihood of life-threatening ventricular arrhythmias is reportedly low, the combination of cardiac ischaemia and specific electrolyte or acid-base abnormalities may increase this risk, particularly in AKI patients who require kidney replacement treatment. The purpose of this review is to summarize the available epidemiological, pathophysiological and prognostic evidence aiming to clarify the complex relationships between AKI and cardiac arrhythmias. © 2022 The Author(s).
dc.language.isoENen_US
dc.title.enThe conundrum of the complex relationship between acute kidney injury and cardiac arrhythmias
dc.typeArticle de revueen_US
dc.identifier.doi10.1093/ndt/gfac210en_US
dc.subject.halSciences du Vivant [q-bio]en_US
bordeaux.journalNephrology Dialysis Transplantationen_US
bordeaux.page1097-1112en_US
bordeaux.volume38en_US
bordeaux.hal.laboratoriesBioingénierie Tissulaire (BioTis) - U1026en_US
bordeaux.issue5en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCHU de Bordeauxen_US
bordeaux.institutionInstitut Bergoniéen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04753344
hal.version1
hal.date.transferred2024-10-25T09:41:47Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Nephrology%20Dialysis%20Transplantation&rft.date=2023&rft.volume=38&rft.issue=5&rft.spage=1097-1112&rft.epage=1097-1112&rft.au=GENOVESI,%20S.&REGOLISTI,%20G.&BURLACU,%20A.&COVIC,%20A.&COMBE,%20C.&rft.genre=article


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