Beyond very early systemic sclerosis: deciphering pre‑scleroderma and its trajectories to open new avenues for preventive medicine
| dc.rights.license | open | en_US |
| dc.contributor.author | LESCOAT, Alain | |
| dc.contributor.author | BELLANDO-RANDONE, Silvia | |
| dc.contributor.author | CAMPOCHIARO, Corrado | |
| dc.contributor.author | DEL GALDO, Francesco | |
| dc.contributor.author | DENTON, Christopher P | |
| dc.contributor.author | FARRINGTON, Sue | |
| dc.contributor.author | GALETTI, Ilaria | |
| dc.contributor.author | KHANNA, Dinesh | |
| dc.contributor.author | KUWANA, Masataka | |
| hal.structure.identifier | Immunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle [ImmunoConcept] | |
| dc.contributor.author | TRUCHETET, Marie-Elise | |
| dc.contributor.author | ALLANORE, Yannick | |
| dc.contributor.author | MATUCCI-CERINIC, Marco | |
| dc.date.accessioned | 2024-09-17T12:10:43Z | |
| dc.date.available | 2024-09-17T12:10:43Z | |
| dc.date.issued | 2023 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/201625 | |
| dc.description.abstractEn | The identification of individuals with systemic sclerosis in an oligosymptomatic phase preceding the very early manifestations of the disease represents a challenge in the search for a new window of opportunity in systemic sclerosis. This phase could be identified in a clinical scenario as the pre-scleroderma phase, in which the disease would still be far from systemic sclerosis-related fibrotic or irreversible manifestations in skin or organs. In this Personal View, we discuss parameters and candidate definitions for a conceptual framework of pre-scleroderma, from the identification of populations at risk to autoantibodies and their potential functional activities. We discuss how this new paradigm of pre-scleroderma could represent a game-changing approach in the management of systemic sclerosis, allowing the treatment of patients at high risk of organ involvement or skin fibrosis before such events occur | |
| dc.language.iso | EN | en_US |
| dc.title.en | Beyond very early systemic sclerosis: deciphering pre‑scleroderma and its trajectories to open new avenues for preventive medicine | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/S2665-9913(23)00212-6 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Immunologie | en_US |
| dc.identifier.pubmed | 38251534 | en_US |
| bordeaux.journal | The Lancet Rheumatology | en_US |
| bordeaux.page | e683-e694 | en_US |
| bordeaux.volume | 5 | en_US |
| bordeaux.hal.laboratories | ImmunoConcEpT - UMR 5164 | en_US |
| bordeaux.issue | 11 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | false | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=The%20Lancet%20Rheumatology&rft.date=2023&rft.volume=5&rft.issue=11&rft.spage=e683-e694&rft.epage=e683-e694&rft.au=LESCOAT,%20Alain&BELLANDO-RANDONE,%20Silvia&CAMPOCHIARO,%20Corrado&DEL%20GALDO,%20Francesco&DENTON,%20Christopher%20P&rft.genre=article |
