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Thermoresponsive Core-cross-linked Nanoparticles from HA--ELP Diblock Copolymers.
| dc.rights.license | open | en_US |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | LEVÊQUE, Manon | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | LECOMMANDOUX, Sébastien | |
| hal.structure.identifier | Laboratoire de Chimie des Polymères Organiques [LCPO] | |
| hal.structure.identifier | Team 3 LCPO : Polymer Self-Assembly & Life Sciences | |
| dc.contributor.author | GARANGER, Elisabeth
IDREF: 089451740 | |
| dc.date.accessioned | 2024-08-19T14:36:44Z | |
| dc.date.available | 2024-08-19T14:36:44Z | |
| dc.date.issued | 2024-05-13 | |
| dc.identifier.issn | 1526-4602 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/201176 | |
| dc.description.abstractEn | Stabilization against the dilution-dependent disassembly of self-assembled nanoparticles is a requirement for application. Herein, we propose a simple and biocompatible cross-linking reaction for the stabilization of a series of nanoparticles formed by the self-assembly of amphiphilic HA--ELP block copolymers, through the alkylation of methionine residues from the ELP block with diglycidyl ether compounds. The core-cross-linked nanoparticles retain their colloidal properties, with a spherical core-shell morphology, while maintaining thermoresponsive behavior. As such, instead of a reversible disassembly when non-cross-linked, a reversible swelling of nanoparticles' core and increase of hydrodynamic diameter are observed with lowering of the temperature. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution-NonCommercial-ShareAlike 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/us/ | * |
| dc.subject.en | Nanoparticles | |
| dc.subject.en | Cross-Linking Reagents | |
| dc.subject.en | Temperature | |
| dc.subject.en | Polymers | |
| dc.subject.en | Elastin | |
| dc.subject.en | Particle Size | |
| dc.title.en | Thermoresponsive Core-cross-linked Nanoparticles from HA--ELP Diblock Copolymers. | |
| dc.title.alternative | Biomacromolecules | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1021/acs.biomac.4c00137 | en_US |
| dc.subject.hal | Chimie/Polymères | en_US |
| dc.identifier.pubmed | 38689515 | en_US |
| bordeaux.journal | Biomacromolecules | en_US |
| bordeaux.page | 3011-3017 | en_US |
| bordeaux.volume | 25 | en_US |
| bordeaux.hal.laboratories | Laboratoire de Chimie des Polymères Organiques (LCPO) - UMR 5629 | en_US |
| bordeaux.issue | 5 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | Bordeaux INP | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | pubmed | |
| hal.identifier | hal-04673008 | |
| hal.version | 1 | |
| hal.date.transferred | 2024-08-19T14:36:46Z | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | true | |
| workflow.import.source | pubmed | |
| dc.rights.cc | CC BY-NC-SA | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Biomacromolecules&rft.date=2024-05-13&rft.volume=25&rft.issue=5&rft.spage=3011-3017&rft.epage=3011-3017&rft.eissn=1526-4602&rft.issn=1526-4602&rft.au=LEV%C3%8AQUE,%20Manon&LECOMMANDOUX,%20S%C3%A9bastien&GARANGER,%20Elisabeth&rft.genre=article |
