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Accuracy of PHQ-9 against psychiatric diagnosis for depression among people living with HIV: A multicounty cross-sectional study

dc.rights.licenseopenen_US
dc.contributor.authorYOTEBIENG, Marcel
dc.contributor.authorZOTOVA, Natalia
hal.structure.identifierBordeaux population health [BPH]
hal.structure.identifierGlobal Health in the Global South [GHiGS]
dc.contributor.authorBERNARD, Charlotte
dc.contributor.authorGOODRICH, Suzanne
dc.contributor.authorAWOH, Ajeh Rogers
dc.contributor.authorWATNICK, Dana
dc.contributor.authorNSONDE, Dominique Mahambu
dc.contributor.authorMOUNGANG, Elodie Flore Tchiengang
dc.contributor.authorNOUMEDEM, Julie Laure Nguemo
dc.contributor.authorMBONGO'O, Guy Calvin Nko'o
dc.contributor.authorMINGA, Albert
dc.contributor.authorSEYDI, Moussa
dc.contributor.authorGANDOU, Paul
dc.contributor.authorKWOBAH, Edith Kamaru
dc.contributor.authorATWOLI, Lukoye
hal.structure.identifierBordeaux population health [BPH]
hal.structure.identifierGlobal Health in the Global South [GHiGS]
dc.contributor.authorJAQUET, Antoine
dc.contributor.authorWOOLS-KALOUSTIAN, Kara
dc.contributor.authorANASTOS, Kathryn
dc.contributor.authorIE, D. E. A. Consortium
dc.date.accessioned2024-07-19T12:10:00Z
dc.date.available2024-07-19T12:10:00Z
dc.date.issued2024-06-21
dc.identifier.issn1473-5571en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/201036
dc.description.abstractEnOBJECTIVE: The aim of this study was to assess the performance of the 9-item Patient Health questionnaire (PHQ-9) against psychiatrist diagnosis in PLWH. DESIGN: Cross-sectional analysis of data collected between January 2018 and July 2022 across five sites in Cameroon, Cote d'Ivoire, Kenya, Senegal, and the Republic of Congo. Participants were ≥18 years and receiving HIV care at the participating site. PHQ-9 was administered by study staff followed by a psychiatrist's evaluation within 3 days. RESULTS: Overall, 778 participants with complete data were included: 297 (38.2%) in Cameroon, 132 (17.0%) in Congo, 148 (19.0%) in Cote d'Ivoire, 98 (12.6%) in Kenya, and 103 (13.2%) in Senegal. The area under the curve for PHQ-9 score was generally high ranging from 0.935 (95% CI: 0.893, 0.977) in Cote d'Ivoire to 0.768 (95% CI: 0.589, 0.947) in Congo. However, for the common cut-off score ≥10, sensitivity was low: 50% or lower in Cameroon, Congo and Senegal, 66.7% in Kenya and 70.6% in Cote d'Ivoire. But negative predictive values (NPV) were high: 98.9% (95% CI: 96.9%, 99.8%) in Cameroon, 96.1 (95% CI: 91.1, 98.7) in Cote d'Ivoire, 96.3% (95% CI: 89.7%, 99.2%) in Kenya, 95.7% (95% CI: 90.2%, 98.6%) in Congo, and 89.0% (95% CI: 81.2%, 94.4%) in Senegal. INTERPRETATION: Across all countries, PHQ-9 score ≥10 performed very poorly (low sensitivity) as a tool to identify psychiatrist diagnosed depression. However, the observed high NPV suggests it can be used to rule out depression.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
dc.subject.enDepression
dc.subject.enPHQ-9
dc.subject.enHIV
dc.subject.ensensitivity
dc.subject.enSpecificity
dc.subject.enSub-Saharan Africa
dc.title.enAccuracy of PHQ-9 against psychiatric diagnosis for depression among people living with HIV: A multicounty cross-sectional study
dc.title.alternativeAIDSen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1097/QAD.0000000000003963en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
dc.identifier.pubmed38905494en_US
bordeaux.journalAIDS. Official journal of the international AIDS Societyen_US
bordeaux.hal.laboratoriesBordeaux Population Health Research Center (BPH) - UMR 1219en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamGHIGS_BPHen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.identifier.funderIDInstitut de Recherche pour le Développementen_US
hal.identifierhal-04654193
hal.version1
hal.date.transferred2024-07-19T12:13:19Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.update.statusnewVersion
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=AIDS.%20Official%20journal%20of%20the%20international%20AIDS%20Society&rft.date=2024-06-21&rft.eissn=1473-5571&rft.issn=1473-5571&rft.au=YOTEBIENG,%20Marcel&ZOTOVA,%20Natalia&BERNARD,%20Charlotte&GOODRICH,%20Suzanne&AWOH,%20Ajeh%20Rogers&rft.genre=article


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