Exposures of zebrafish through diet to three environmentally relevant mixtures of PAHs produce behavioral disruptions in unexposed F1 and F2 descendant.
| dc.rights.license | open | en_US |
| hal.structure.identifier | Unité Biogéochimie et Ecotoxicologie [BE] | |
| dc.contributor.author | VIGNET, Caroline | |
| hal.structure.identifier | Laboratoire Ressources Halieutiques de Boulogne [LRHBL] | |
| dc.contributor.author | JOASSARD, Lucette | |
| hal.structure.identifier | Laboratoire Ressources Halieutiques de Boulogne [LRHBL] | |
| dc.contributor.author | LYPHOUT, Laura | |
| hal.structure.identifier | Laboratoire Ressources Halieutiques de Boulogne [LRHBL] | |
| dc.contributor.author | GUIONNET, Tiphaine | |
| hal.structure.identifier | Unité Biogéochimie et Ecotoxicologie [BE] | |
| dc.contributor.author | GOUBEAU, Manon | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | LE MENACH, Karyn
IDREF: 256879966 | |
| hal.structure.identifier | Institut National de l'Environnement Industriel et des Risques [INERIS] | |
| dc.contributor.author | BRION, François | |
| hal.structure.identifier | Institut de recherche en santé, environnement et travail [Irset] | |
| dc.contributor.author | KAH, Olivier | |
| hal.structure.identifier | Institute of Molecular Biology [IMB Sinica] | |
| dc.contributor.author | CHUNG, Bon-Chu | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | BUDZINSKI, Hélène
ORCID: 0000-0003-1028-9154 IDREF: 070478090 | |
| hal.structure.identifier | Laboratoire Ressources Halieutiques de Boulogne [LRHBL] | |
| dc.contributor.author | BÉGOUT, Marie-Laure | |
| hal.structure.identifier | Unité Biogéochimie et Ecotoxicologie [BE] | |
| hal.structure.identifier | Laboratoire de Physiologie et Génomique des Poissons [LPGP] | |
| dc.contributor.author | COUSIN, Xavier | |
| dc.date.accessioned | 2024-06-19T07:39:56Z | |
| dc.date.available | 2024-06-19T07:39:56Z | |
| dc.date.issued | 2015-02-03 | |
| dc.identifier.issn | 0944-1344 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/200563 | |
| dc.description.abstractEn | The release of polycyclic aromatic hydrocarbons (PAHs) into the environment has increased very substantially over the last decades. PAHs are hydrophobic molecules which can accumulate in high concentrations in sediments acting then as major secondary sources. Fish contamination can occur through contact or residence nearby sediments or though dietary exposure. In this study, we analyzed certain physiological traits in unexposed fish (F1) issued from parents (F0) exposed through diet to three PAH mixtures at similar and environmentally relevant concentrations but differing in their compositions. For each mixture, no morphological differences were observed between concentrations. An increase in locomotor activity was observed in larvae issued from fish exposed to the highest concentration of a pyrolytic (PY) mixture. On the contrary, a decrease in locomotor activity was observed in larvae issued from heavy oil mixture (HO). In the case of the third mixture, light oil (LO), a reduction of the diurnal activity was observed during the setup of larval activity. Behavioral disruptions persisted in F1-PY juveniles and in their offspring (F2). Endocrine disruption was analyzed using cyp19a1b:GFP transgenic line and revealed disruptions in PY and LO offspring. Since no PAH metabolites were dosed in larvae, these findings suggest possible underlying mechanisms such as altered parental signaling molecule and/or hormone transferred in the gametes, eventually leading to early imprinting. Taken together, these results indicate that physiological disruptions are observed in offspring of fish exposed to PAH mixtures through diet. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Danio rerio | |
| dc.subject.en | polycyclic aromatic hydrocarbon | |
| dc.subject.en | offspring | |
| dc.subject.en | transgenerational effect | |
| dc.subject.en | heavy oil | |
| dc.subject.en | light crude oil | |
| dc.subject.en | locomotor activity | |
| dc.subject.en | photomotor response | |
| dc.subject.en | anxiety-like behavior | |
| dc.title.en | Exposures of zebrafish through diet to three environmentally relevant mixtures of PAHs produce behavioral disruptions in unexposed F1 and F2 descendant. | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1007/s11356-015-4157-8 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Ecologie, Environnement | en_US |
| bordeaux.journal | Environmental Science and Pollution Research | en_US |
| bordeaux.page | 16371–16383 | en_US |
| bordeaux.volume | 22 | en_US |
| bordeaux.hal.laboratories | EPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805 | en_US |
| bordeaux.issue | 21 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.team | LPTC | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | hal | |
| hal.identifier | hal-01121865 | |
| hal.version | 1 | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | false | |
| workflow.import.source | hal | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Environmental%20Science%20and%20Pollution%20Research&rft.date=2015-02-03&rft.volume=22&rft.issue=21&rft.spage=16371%E2%80%9316383&rft.epage=16371%E2%80%9316383&rft.eissn=0944-1344&rft.issn=0944-1344&rft.au=VIGNET,%20Caroline&JOASSARD,%20Lucette&LYPHOUT,%20Laura&GUIONNET,%20Tiphaine&GOUBEAU,%20Manon&rft.genre=article |
