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Bioactive Endodontic Hydrogels: From Parameters to Personalized Medicine

dc.rights.licenseopenen_US
dc.contributor.authorLEVEQUE, M.
dc.contributor.authorBEKHOUCHE, M.
dc.contributor.authorFARGES, J.-C.
dc.contributor.authorSY, K.
dc.contributor.authorRICHERT, R.
dc.contributor.authorDUCRET, M.
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
dc.contributor.authorAUSSEL, Audrey
dc.date.accessioned2024-06-06T07:26:53Z
dc.date.available2024-06-06T07:26:53Z
dc.date.issued2023
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/200294
dc.description.abstractEnRegenerative endodontic procedures (REPs) aim at recreating dental pulp tissue using biomaterials such as hydrogels. Their bioactivity is mostly related to the nature of biomolecules or chemical compounds that compose the endodontic hydrogel. However, many other parameters, such as hydrogel concentration, bioactive molecules solubility, and apex size, were reported to influence the reciprocal host–biomaterial relationship and hydrogel behavior. The lack of knowledge regarding these various parameters, which should be considered, leads to the inability to predict the clinical outcome and suggests that the biological activity of endodontic hydrogel is impossible to anticipate and could hinder the bench-to-bedside transition. We describe, in this review, that most of these parameters could be identified, described, and studied. A second part of the review lists some challenges and perspectives, including development of future mathematical models that are able to explain, and eventually predict, the bioactivity of endodontic hydrogel used in a clinical setting. © 2023 by the authors.
dc.language.isoENen_US
dc.title.enBioactive Endodontic Hydrogels: From Parameters to Personalized Medicine
dc.typeArticle de revueen_US
dc.identifier.doi10.3390/ijms241814056en_US
dc.subject.halSciences du Vivant [q-bio]en_US
bordeaux.journalInternational Journal of Molecular Sciencesen_US
bordeaux.volume24en_US
bordeaux.hal.laboratoriesBioingénierie Tissulaire (BioTis) - U1026en_US
bordeaux.issue18en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCHU de Bordeauxen_US
bordeaux.institutionInstitut Bergoniéen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04602931
hal.version1
hal.date.transferred2024-06-06T07:26:54Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
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