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Home-based exercise in patients on maintenance dialysis : Asystematic review and meta-analysis of randomized clinical trials

dc.rights.licenseopenen_US
dc.contributor.authorBATTAGLIA, Y.
dc.contributor.authorAMICONE, M.
dc.contributor.authorMANTOVANI, A.
dc.contributor.authorMITRA, S.
dc.contributor.authorBASILE, C.
dc.contributor.authorERA, EuDial Working Group Of
hal.structure.identifierHôpital Pellegrin
hal.structure.identifierService de Néphrologie-Transplantation-Dialyse
hal.structure.identifierBioingénierie tissulaire [BIOTIS]
hal.structure.identifierCentre Hospitalier Universitaire de Bordeaux [CHU Bordeaux]
hal.structure.identifierCHU de Bordeaux Pellegrin [Bordeaux]
hal.structure.identifierService de Néphrologie-transplantation-dialyse [Bordeaux]
dc.contributor.authorCOMBE, Christian
ORCID: 0000-0002-0360-573X
IDREF: 58708871
dc.date.accessioned2024-06-05T08:27:54Z
dc.date.available2024-06-05T08:27:54Z
dc.date.issued2023
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/200284
dc.description.abstractEnBackground. The impact of home-based exercise on physical performance and quality of life (QoL) in patients on maintenance dialysis has not yet been fully established. Methods. We searched four large electronic databases to identify randomized controlled trials (RCTs) reporting the impact of home-based exercise interventions vs. usual care or intradialytic exercise interventions, on physical performance and QoL in patients on dialysis. The meta-analysis was performed using fixed effects modeling. Results. We included 12 unique RCTs involving 791 patients of various ages on maintenance dialysis. Home-based exercise interventions were associated with an improvement of walking speed at the 6 Minutes Walking Test [6MWT; nine RCTs; pooled weighted mean differences (WMD): 33.7 m, 95% confidence interval (CI) 22.8–44.5; P < 0.001; I2 = 0%) and in aerobic capacity as assessed by the peak oxygen consumption (VO2 peak; 3 RCTs; pooled WMD: 2.04 ml/kg/min, 95% CI 0.25–3.83; P = 0.03; I2 = 0%). They were also associated with improved QoL, as assessed by the Short Form (36) Health (SF-36) score. Stratifying the RCTs by control groups, no significant difference was found between home-based exercise and intradialytic exercise interventions. Funnel plots did not reveal any significant publication bias. Conclusions. Our systematic review and meta-analysis showed that home-based exercise interventions for 3–6 months were associated with significant improvements in physical performance in patients on maintenance dialysis. However, further RCTs with a longer follow-up should be conducted to assess the safety, adherence, feasibility, and effects on QoL of home-based exercise programs in dialysis patients. © 2023 Oxford University Press. All rights reserved.
dc.language.isoENen_US
dc.titleHome-based exercise in patients on maintenance dialysis : Asystematic review and meta-analysis of randomized clinical trials
dc.typeArticle de revueen_US
dc.identifier.doi10.1093/ndt/gfad102en_US
dc.subject.halSciences du Vivant [q-bio]en_US
bordeaux.journalNephrology Dialysis Transplantationen_US
bordeaux.page2550-2561en_US
bordeaux.volume38en_US
bordeaux.hal.laboratoriesBioingénierie Tissulaire (BioTis) - U1026en_US
bordeaux.issue11en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.institutionINSERMen_US
bordeaux.institutionCHU de Bordeauxen_US
bordeaux.institutionInstitut Bergoniéen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.identifierhal-04601644
hal.version1
hal.date.transferred2024-06-05T08:27:56Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
dc.rights.ccPas de Licence CCen_US
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