Impact of drug consumption rooms on non-fatal overdoses, abscesses and emergency department visits in people who inject drugs in France: results from the COSINUS cohort
| dc.rights.license | open | en_US |
| hal.structure.identifier | Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale [SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD] | |
| hal.structure.identifier | Institut des sciences de la santé publique [Marseille] [ISSPAM] | |
| dc.contributor.author | ROUX, P | |
| hal.structure.identifier | CERMES3 - Centre de recherche Médecine, sciences, santé, santé mentale, société [CERMES3 - UMR 8211 / U988 / UM 7] | |
| hal.structure.identifier | British Columbia | |
| hal.structure.identifier | State University of New York [Buffalo] | |
| dc.contributor.author | JAUFFRET-ROUSTIDE, M | |
| hal.structure.identifier | Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale [SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD] | |
| hal.structure.identifier | Institut des sciences de la santé publique [Marseille] [ISSPAM] | |
| dc.contributor.author | DONADILLE, C | |
| hal.structure.identifier | Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale [SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD] | |
| hal.structure.identifier | Institut des sciences de la santé publique [Marseille] [ISSPAM] | |
| dc.contributor.author | BRIAND MADRID, L | |
| hal.structure.identifier | University of Pennsylvania | |
| hal.structure.identifier | Université de Bordeaux [UB] | |
| hal.structure.identifier | Sommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY] | |
| hal.structure.identifier | Centre hospitalier Charles Perrens [Bordeaux] | |
| dc.contributor.author | DENIS, C | |
| hal.structure.identifier | Observatoire régional de la santé Provence-Alpes-Côte d'Azur [Marseille] [ORS PACA] | |
| dc.contributor.author | CÉLÉRIER, I | |
| hal.structure.identifier | CERMES3 - Centre de recherche Médecine, sciences, santé, santé mentale, société [CERMES3 - UMR 8211 / U988 / UM 7] | |
| dc.contributor.author | CHAUVIN, C | |
| hal.structure.identifier | Neuropsychologie Cognitive et Physiopathologie de la Schizophrénie [NCPS] | |
| dc.contributor.author | HAMELIN, N | |
| hal.structure.identifier | Observatoire régional de la santé Provence-Alpes-Côte d'Azur [Marseille] [ORS PACA] | |
| dc.contributor.author | MARADAN, G | |
| hal.structure.identifier | Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale [SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD] | |
| hal.structure.identifier | Institut des sciences de la santé publique [Marseille] [ISSPAM] | |
| dc.contributor.author | CARRIERI, M | |
| hal.structure.identifier | Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale [SESSTIM - U1252 INSERM - Aix Marseille Univ - UMR 259 IRD] | |
| hal.structure.identifier | Institut des sciences de la santé publique [Marseille] [ISSPAM] | |
| dc.contributor.author | PROTOPOPESCU, C | |
| hal.structure.identifier | Neuropsychologie Cognitive et Physiopathologie de la Schizophrénie [NCPS] | |
| hal.structure.identifier | Fédération de Médecine Translationnelle de Strasbourg [FMTS] | |
| dc.contributor.author | LALANNE, L | |
| hal.structure.identifier | Sommeil, Addiction et Neuropsychiatrie [Bordeaux] [SANPSY] | |
| dc.contributor.author | AURIACOMBE, Marc
ORCID: 0000-0002-8938-8683 IDREF: 033753210 | |
| dc.date.accessioned | 2024-06-05T07:33:45Z | |
| dc.date.available | 2024-06-05T07:33:45Z | |
| dc.date.issued | 2023-04-19 | |
| dc.identifier.issn | 0300-5771 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/200276 | |
| dc.description.abstractEn | Background: The effectiveness of drug consumption rooms (DCRs) for people who inject drugs (PWID) has been demonstrated for HIV and hepatitis C virus risk practices, and access to care for substance use disorders. However, data on other health-related complications are scarce. Using data from the French COSINUS cohort, we investigated the impact of DCR exposure on non-fatal overdoses, abscesses and emergency department (ED) visits, all in the previous 6 months.Methods: COSINUS is a 12-month prospective cohort study of 665 PWID in France studying DCR effectiveness on health. We collected data from face-to-face interviews at enrolment, and at 6 and 12 months of follow-up. After adjusting for other correlates (P-value < 0.05), the impact of DCR exposure on each outcome was assessed using a two-step Heckman mixed-effects probit model, allowing us to adjust for potential non-randomization bias due to differences between DCR-exposed and DCR-unexposed participants, while taking into account the correlation between repeated measures.Results: At enrolment, 21%, 6% and 38% of the 665 participants reported overdoses, abscesses and ED visits, respectively. Multivariable models found that DCR-exposed participants were less likely to report overdoses [adjusted coefficient (95% CI): -0.47 (-0.88; -0.07), P = 0.023], abscesses [-0.74 (-1.11; -0.37), P < 0.001] and ED visits [-0.74 (-1.27; -0.20), P = 0.007].Conclusion: This is the first study to show the positive impact of DCR exposure on abscesses and ED visits, and confirms DCR effectiveness in reducing overdoses, when adjusting for potential non-randomization bias. Our findings strengthen the argument to expand DCR implementation to improve PWID injection environment and health. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Safer injecting facility | |
| dc.subject.en | injection drug users | |
| dc.subject.en | risk environment | |
| dc.subject.en | abscess | |
| dc.subject.en | overdose | |
| dc.subject.en | emergency department | |
| dc.subject.en | skin and soft tissue infections | |
| dc.title.en | Impact of drug consumption rooms on non-fatal overdoses, abscesses and emergency department visits in people who inject drugs in France: results from the COSINUS cohort | |
| dc.title.alternative | Int J Epidemiol | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1093/ije/dyac120 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 35690956 | en_US |
| bordeaux.journal | International Journal of Epidemiology | en_US |
| bordeaux.page | 562 - 576 | en_US |
| bordeaux.volume | 52 | en_US |
| bordeaux.hal.laboratories | SANPSY (Sommeil, Addiction, Neuropsychiatrie) - UMR 6033 | en_US |
| bordeaux.issue | 2 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | hal | |
| hal.identifier | inserm-04312540 | |
| hal.version | 1 | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | false | |
| workflow.import.source | hal | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=International%20Journal%20of%20Epidemiology&rft.date=2023-04-19&rft.volume=52&rft.issue=2&rft.spage=562%20-%20576&rft.epage=562%20-%20576&rft.eissn=0300-5771&rft.issn=0300-5771&rft.au=ROUX,%20P&JAUFFRET-ROUSTIDE,%20M&DONADILLE,%20C&BRIAND%20MADRID,%20L&DENIS,%20C&rft.genre=article |
Files in this item
| Files | Size | Format | View |
|---|---|---|---|
|
There are no files associated with this item. |
|||