Environmental concentrations of benz[a]anthracene induce developmental defects and DNA damage and impair photomotor response in Japanese medaka larvae.
| dc.rights.license | open | en_US |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | LE BIHANIC, Florane | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | SOMMARD, Vivien | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | PERRINE, De Lansalut | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | PICHON, Anaik | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | GRASSET, Julie | |
| hal.structure.identifier | Atoxigen Laboratory | |
| dc.contributor.author | BERRADA, Saadia | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | BUDZINSKI, Hélène
ORCID: 0000-0003-1028-9154 IDREF: 070478090 | |
| hal.structure.identifier | Laboratoire de Physiologie et Génomique des Poissons [LPGP] | |
| hal.structure.identifier | Unité Biogéochimie et Ecotoxicologie [BE] | |
| dc.contributor.author | COUSIN, Xavier | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | MORIN, Benedicte
IDREF: 178000892 | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | CACHOT, Jérôme
ORCID: 0000-0002-1492-9684 IDREF: 19667672X | |
| dc.date.accessioned | 2024-05-29T09:44:57Z | |
| dc.date.available | 2024-05-29T09:44:57Z | |
| dc.date.issued | 2015-03 | |
| dc.identifier.issn | 0147-6513 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/200122 | |
| dc.description.abstractEn | Benz[a]anthracene (BaA) is a ubiquitous polycyclic aromatic hydrocarbon found in numerous aquatic ecosystems. However, ecotoxicological data in aquatic organisms are scarce. To remedy this lack of data, Japanese medaka (Oryzias latipes) embryos were exposed to BaA and toxic effects were investigated at multiple toxicological endpoints. Japanese medaka embryos were incubated onto BaA-spiked artificial sediment for 9 days at low or moderate environmental concentrations ranging from 0.9 to 12µgg(-1) dw. BaA-exposed embryos exhibited significant tachycardia. BaA exposure was also shown to increase CYP1A activity in the hepato-biliary tissue as well as craniofacial deformities and DNA damage in pro-larvae. The photomotor response of BaA-exposed larvae was reduced in comparison to the control group. According to this set of tests, the lowest tested and observed effect concentration (LOEC) for Japanese medaka early life stages was equivalent to 0.92µgg(-1) dw of BaA. This concentration fall into the range of concentrations frequently encountered in sediments of polluted aquatic ecosystems. Taking into consideration these results, BaA represents a threat for fish early life stages in particular those developing onto or into contaminated sediments. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | benz[a]anthracene | |
| dc.subject.en | spiked sediment | |
| dc.subject.en | swimming behavior | |
| dc.subject.en | teratogenicity | |
| dc.subject.en | dna damage | |
| dc.subject.en | in vivo erod activity | |
| dc.title.en | Environmental concentrations of benz[a]anthracene induce developmental defects and DNA damage and impair photomotor response in Japanese medaka larvae. | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1016/j.ecoenv.2014.12.011 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Toxicologie/Ecotoxicologie | en_US |
| bordeaux.journal | Ecotoxicology and Environmental Safety | en_US |
| bordeaux.page | 321-328 | en_US |
| bordeaux.volume | 113C | en_US |
| bordeaux.hal.laboratories | EPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | CNRS | en_US |
| bordeaux.team | EA | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.import.source | hal | |
| hal.identifier | hal-01205116 | |
| hal.version | 1 | |
| hal.popular | non | en_US |
| hal.audience | Non spécifiée | en_US |
| hal.export | false | |
| workflow.import.source | hal | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Ecotoxicology%20and%20Environmental%20Safety&rft.date=2015-03&rft.volume=113C&rft.spage=321-328&rft.epage=321-328&rft.eissn=0147-6513&rft.issn=0147-6513&rft.au=LE%20BIHANIC,%20Florane&SOMMARD,%20Vivien&PERRINE,%20De%20Lansalut&PICHON,%20Anaik&GRASSET,%20Julie&rft.genre=article |
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