Assessment of adherence to the 2020 Surviving Sepsis Campaign guidelines for fluid resuscitation in children with suspected septic shock in paediatric emergency departments: a prospective multicentre study
| dc.rights.license | open | en_US |
| dc.contributor.author | SAN GEROTEO, Julian | |
| dc.contributor.author | LEVY, Michael | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | BAILHACHE, Marion | |
| dc.contributor.author | DE JORNA, Claire | |
| dc.contributor.author | PRIVAT, Elodie | |
| dc.contributor.author | GASMI, Oussama | |
| dc.contributor.author | FUENTES-LOPEZ, Maria | |
| dc.contributor.author | LAOUDI, Yacine | |
| dc.contributor.author | MAZEGHRANE, Mustapha | |
| dc.contributor.author | MALTERRE, Aline | |
| dc.contributor.author | BORIES, Pauline | |
| dc.contributor.author | ABDEL AAL, Khaled | |
| dc.contributor.author | ARJOCA, Iozefina | |
| dc.contributor.author | GASCHIGNARD, Jean | |
| dc.contributor.author | TANCHALEUNE, Davy | |
| dc.contributor.author | MINODIER, Philippe | |
| dc.contributor.author | AUDREN, Fabien | |
| dc.contributor.author | MAZETIER, Tifanny | |
| dc.contributor.author | QUAGLIARO, Pauline | |
| dc.contributor.author | RAIMOND, Florence | |
| dc.contributor.author | SIENG, Soria | |
| dc.contributor.author | ROBERT, Blandine | |
| dc.contributor.author | WOHRER, Delphine | |
| dc.contributor.author | DE SUREMAIN, Nathalie | |
| dc.contributor.author | DAUGER, Stephane | |
| dc.date.accessioned | 2024-05-07T06:58:28Z | |
| dc.date.available | 2024-05-07T06:49:17Z | |
| dc.date.available | 2024-05-07T06:58:28Z | |
| dc.date.issued | 2024-03-18 | |
| dc.identifier.issn | 0003-9888 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/199685.2 | |
| dc.description.abstractEn | BACKGROUND: Paediatric sepsis is the leading cause of death in children under 5 years. No studies have evaluated the application of the Surviving Sepsis Campaign 2020 (SSC-2020) guidelines in paediatric emergency departments (PEDs). OBJECTIVE: To assess physician adherence to the SSC-2020 fluid resuscitation guidelines in children with suspected septic shock in PEDs. METHODS: This was a prospective multicentre observational study conducted in 21 French hospitals over 5 sequential weeks, between November 2021 and March 2022. Children with suspected septic shock and who received antimicrobial therapy within 72 hours were included. Primary outcome was SSC-2020 fluid resuscitation guidelines adherence (low 0-24%; moderate 25-74%; high 75-100%) according to: bolus volume of 10-20 mL/kg each, exclusive administration of balanced crystalloids at 1 and 24 hours of management, and initiation of fluid resuscitation within 1 hour of septic shock recognition. RESULTS: 63 children were included. 10 (16%) children had severe sepsis and 2 (3%) met the definition of septic shock. Compared with the SSC-2020 guidelines, 43 (68%) patients received boluses of 10-20 mL/kg; fluid resuscitation was initiated within 1 hour of septic shock recognition in 42 (76%) cases; balanced crystalloids were the only fluids administrated in 35 (56%) and 34 (55%) children at 1 and 24 hours of management, respectively. Main barriers reported by physicians were difficult intravenous access (43%), lack of team training (29%), workload constraints (28%), and absence or out-of-date protocols (24%). CONCLUSIONS: This study found high adherence for fluid resuscitation initiation but moderate adherence for bolus volume and fluid choice. TRIAL REGISTRATION NUMBER: NCT05066464. | |
| dc.language.iso | EN | en_US |
| dc.subject.en | Emergency Care | |
| dc.subject.en | Intensive Care Units | |
| dc.subject.en | Paediatric | |
| dc.subject.en | Paediatric Emergency Medicine | |
| dc.subject.en | Paediatrics | |
| dc.subject.en | Sepsis | |
| dc.title.en | Assessment of adherence to the 2020 Surviving Sepsis Campaign guidelines for fluid resuscitation in children with suspected septic shock in paediatric emergency departments: a prospective multicentre study | |
| dc.title.alternative | Arch Dis Child | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1136/archdischild-2023-325837 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 38499323 | en_US |
| bordeaux.journal | Archives of Disease in Childhood | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | HEALTHY_BPH | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-04570295 | |
| hal.version | 1 | |
| hal.date.transferred | 2024-05-07T06:58:33Z | |
| hal.popular | non | en_US |
| hal.audience | Internationale | en_US |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Archives%20of%20Disease%20in%20Childhood&rft.date=2024-03-18&rft.eissn=0003-9888&rft.issn=0003-9888&rft.au=SAN%20GEROTEO,%20Julian&LEVY,%20Michael&BAILHACHE,%20Marion&DE%20JORNA,%20Claire&PRIVAT,%20Elodie&rft.genre=article |
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