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A Novel Tool to Identify Bactericidal Compounds against Vulnerable Targets in Drug-Tolerant M. tuberculosis found in Caseum

dc.rights.licenseopenen_US
dc.contributor.authorSARATHY, Jansy
dc.contributor.authorXIE, Min
dc.contributor.authorJONES, Richard
dc.contributor.authorCHANG, Adrienne
dc.contributor.authorOSIECKI, Paulina
dc.contributor.authorWEINER, Danielle
dc.contributor.authorTSAO, Wen-Shan
dc.contributor.authorDOUGHER, Maureen
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorBLANC, Landry
dc.contributor.authorFOTOUHI, Nader
dc.contributor.authorVIA, Laura
dc.contributor.authorBARRY, Clifton
dc.contributor.authorDE VLAMINCK, Iwijn
dc.contributor.authorSHERMAN, David
dc.contributor.authorDARTOIS, Veronique
dc.date.accessioned2024-04-24T08:43:55Z
dc.date.available2024-04-24T08:43:55Z
dc.date.issued2023-04-25
dc.identifier.issn2161-2129en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/199290
dc.description.abstractEnM. tuberculosis (Mtb) within the caseous core of necrotic granulomas and cavities is extremely drug tolerant and presents a significant hurdle to treatment success and relapse prevention. Many in vitro models of nonreplicating persistence have been developed to characterize the physiologic and metabolic adaptations of Mtb and identify compounds active against this treatment-recalcitrant population.
dc.language.isoENen_US
dc.title.enA Novel Tool to Identify Bactericidal Compounds against Vulnerable Targets in Drug-Tolerant M. tuberculosis found in Caseum
dc.typeArticle de revueen_US
dc.identifier.doi10.1128/mbio.00598-23en_US
dc.subject.halSciences du Vivant [q-bio]/Sciences pharmaceutiques/Pharmacologieen_US
bordeaux.journalmBioen_US
bordeaux.volume14en_US
bordeaux.hal.laboratoriesCBMN : Chimie & de Biologie des Membranes & des Nano-objets - UMR 5248en_US
bordeaux.issue2en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-04248670
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccPas de Licence CCen_US
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