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Comparative responses of sperm cells and embryos of Pacific oyster (Crassostrea gigas) to exposure to metolachlor and its degradation products

dc.rights.licenseopenen_US
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorMAI, Huong
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorGONZALEZ, Patrice
ORCID: 0000-0003-2628-2993
IDREF: 14341917X
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorPARDON, Patrick
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorTAPIE, Nathalie
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorBUDZINSKI, Hélène
ORCID: 0000-0003-1028-9154
IDREF: 070478090
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorCACHOT, Jérôme
ORCID: 0000-0002-1492-9684
IDREF: 19667672X
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorMORIN, Benedicte
IDREF: 178000892
dc.date.accessioned2024-04-16T09:29:32Z
dc.date.available2024-04-16T09:29:32Z
dc.date.issued2013-12-07
dc.identifier.issn0166-445Xen_US
dc.identifier.urihttps://www.researchgate.net/publication/259498784_Comparative_responses_of_sperm_cells_and_embryos_of_Pacific_oyster_Crassostrea_gigas_to_exposure_to_metolachlor_and_its_degradation_products
dc.identifier.urioai:crossref.org:10.1016/j.aquatox.2013.11.024
dc.identifier.urioai:researchgate.net:259498784
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/199084
dc.description.abstractEnMetolachlor is one of the most intensively used chloroacetanilide herbicides in agriculture. Consequently, it has been frequently detected in coastal waters as well as its major degradation products, metolachlor ethane sulfonic acid (MESA) and metolachlor oxanilic acid (MOA) which are encountered at higher concentrations than metolachlor. Although a few studies of metolachlor toxicity have been conducted on marine organisms, little is known about the environmental toxicity of metolachlor degradation products. In this study, the deleterious effects of metolachlor and its degradation products on spermatozoa and embryos of Crassostrea gigas have been compared using biomarkers of developmental defects, DNA damage and gene transcription levels. After 24h exposure, significant increases in the percentage of abnormal D-larvae and DNA damage were observed from 0.01μgL(-1) for S-metolachlor and 0.1μgL(-1) for MESA and MOA. Results showed that S-metolachlor was more embryotoxic and genotoxic than its degradation products. Oyster sperm was also very sensitive to metolachlor exposure and followed the pattern: metolachlor (0.01μgL(-1))>MOA (0.1μgL(-1))>MESA (1μgL(-1)). Metolachlor and MESA mainly triggered variations in the transcription level of genes encoding proteins involved in oxidative stress responses (mitochondrial superoxide dismutase and catalase). Overall, no significant variation in transcription levels could be detected in C. gigas embryos exposed to MOA. This study demonstrates that metolachlor and its main degradation products have the potential to impact several steps of oyster development and therefore recruitment in coastal areas exposed to chronic inputs of pesticides.
dc.language.isoENen_US
dc.sourcecrossref
dc.sourceresearchgate
dc.title.enComparative responses of sperm cells and embryos of Pacific oyster (Crassostrea gigas) to exposure to metolachlor and its degradation products
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.aquatox.2013.11.024en_US
dc.subject.halSciences de l'environnementen_US
bordeaux.journalAquatic Toxicologyen_US
bordeaux.page48-56en_US
bordeaux.volume147en_US
bordeaux.hal.laboratoriesEPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.teamEAen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcedissemin
hal.identifierhal-04548088
hal.version1
hal.date.transferred2024-04-16T09:29:34Z
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exporttrue
workflow.import.sourcedissemin
dc.rights.ccPas de Licence CCen_US
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