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Genetic control of abiotic stress-related specialized metabolites in sunflower

hal.structure.identifierLaboratoire des Interactions Plantes Microbes Environnement [LIPME]
dc.contributor.authorMOROLDO, Marco
hal.structure.identifierLaboratoire des Interactions Plantes Microbes Environnement [LIPME]
dc.contributor.authorBLANCHET, Nicolas
hal.structure.identifierLaboratoire des Interactions Plantes Microbes Environnement [LIPME]
hal.structure.identifierBiologie intégrée pour la valorisation de la diversité des Arbres et de la Forêt [BioForA]
dc.contributor.authorDURUFLÉ, Harold
hal.structure.identifierUnité de recherche Mycologie et Sécurité des Aliments [MycSA]
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorBERNILLON, Stéphane
hal.structure.identifierBiologie du fruit et pathologie [BFP]
dc.contributor.authorBERTON, Thierry
hal.structure.identifierBiologie du fruit et pathologie [BFP]
hal.structure.identifierRésistance Induite et Bioprotection des Plantes - EA 4707 [RIBP]
dc.contributor.authorFERNANDEZ, Olivier
hal.structure.identifierBiologie du fruit et pathologie [BFP]
hal.structure.identifierPlateforme Bordeaux Metabolome
dc.contributor.authorGIBON, Yves
hal.structure.identifierBiologie du fruit et pathologie [BFP]
hal.structure.identifierPlateforme Bordeaux Metabolome
dc.contributor.authorMOING, Annick
hal.structure.identifierInstitut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement [INRAE]
hal.structure.identifierLaboratoire des Interactions Plantes Microbes Environnement [LIPME]
dc.contributor.authorLANGLADE, Nicolas
dc.date.issued2024-02-20
dc.identifier.issn1471-2164
dc.description.abstractEnAbiotic stresses in plants include all the environmental conditions that significantly reduce yields, like drought and heat. One of the most significant effects they exert at the cellular level is the accumulation of reactive oxygen species, which cause extensive damage. Plants possess two mechanisms to counter these molecules, i.e. detoxifying enzymes and non-enzymatic antioxidants, which include many classes of specialized metabolites. Sunflower, the fourth global oilseed, is considered moderately drought resistant. Abiotic stress tolerance in this crop has been studied using many approaches, but the control of specialized metabolites in this context remains poorly understood. Here, we performed the first genome-wide association study using abiotic stress-related specialized metabolites as molecular phenotypes in sunflower. After analyzing leaf specialized metabolites of 450 hybrids using liquid chromatography-mass spectrometry, we selected a subset of these compounds based on their association with previously known abiotic stress-related quantitative trait loci. Eventually, we characterized these molecules and their associated genes. We putatively annotated 30 compounds which co-localized with abiotic stress-related quantitative trait loci and which were associated to seven most likely candidate genes. A large proportion of these compounds were potential antioxidants, which was in agreement with the role of specialized metabolites in abiotic stresses. The seven associated most likely candidate genes, instead, mainly belonged to cytochromes P450 and glycosyltransferases, two large superfamilies which catalyze greatly diverse reactions and create a wide variety of chemical modifications. This was consistent with the high plasticity of specialized metabolism in plants. This is the first characterization of the genetic control of abiotic stress-related specialized metabolites in sunflower. By providing hints concerning the importance of antioxidant molecules in this biological context, and by highlighting some of the potential molecular mechanisms underlying their biosynthesis, it could pave the way for novel applications in breeding. Although further analyses will be required to better understand this topic, studying how antioxidants contribute to the tolerance to abiotic stresses in sunflower appears as a promising area of research.
dc.description.sponsorshipRessources génétiques de tournesol pour l'amélioration de la stabilité de production d'huile sous c
dc.description.sponsorshipCentre français de phénomique végétale - ANR-11-INBS-0012
dc.description.sponsorshipDéveloppement d'une infrastructure française distribuée pour la métabolomique dédiée à l'innovation - ANR-11-INBS-0010
dc.description.sponsorshipTowards a Unified theory of biotic Interactions: the roLe of environmental - ANR-10-LABX-0041
dc.description.sponsorshipUniversité Fédérale de Toulouse - ANR-11-IDEX-0002
dc.language.isoen
dc.publisherBioMed Central
dc.rights.urihttp://creativecommons.org/licenses/by/
dc.subject.enSunflower (Helianthus annuus)
dc.subject.enAbiotic stresses
dc.subject.enMetabolome
dc.subject.enLiquid chromatography-mass spectrometry
dc.subject.enGenome-wide association study
dc.subject.enAntioxidants
dc.subject.enSpecialized metabolites
dc.subject.enReactive oxygen species
dc.title.enGenetic control of abiotic stress-related specialized metabolites in sunflower
dc.typeArticle de revue
dc.identifier.doi10.1186/s12864-024-10104-9
dc.subject.halSciences de l'environnement
dc.subject.halInformatique [cs]/Modélisation et simulation
dc.subject.halSciences du Vivant [q-bio]/Biochimie, Biologie Moléculaire/Génomique, Transcriptomique et Protéomique [q-bio.GN]
dc.subject.halSciences du Vivant [q-bio]/Biotechnologies
dc.subject.halSciences du Vivant [q-bio]/Biologie végétale
dc.subject.halSciences du Vivant [q-bio]/Biologie végétale/Botanique
dc.subject.halSciences du Vivant [q-bio]/Sciences agricoles/Sciences et techniques de l'agriculture
bordeaux.journalBMC Genomics
bordeaux.page199
bordeaux.volume25
bordeaux.issue1
bordeaux.peerReviewedoui
hal.identifierhal-04468891
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-04468891v1
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