Fish Reproduction Is Disrupted upon Lifelong Exposure to Environmental PAHs Fractions Revealing Different Modes of Action
| hal.structure.identifier | Unité Biogéochimie et Ecotoxicologie [BE] | |
| dc.contributor.author | VIGNET, Caroline | |
| hal.structure.identifier | Physiopathologie Animale et bioThérapie du muscle et du système nerveux [PAnTher] | |
| dc.contributor.author | LARCHER, Thibaut | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | DAVAIL, Blandine | |
| hal.structure.identifier | Laboratoire Ressources Halieutiques La Rochelle-L'Houmeau [ LRHLR] | |
| dc.contributor.author | JOASSARD, Lucette | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | LE MENACH, Karyn | |
| hal.structure.identifier | Laboratoire Ressources Halieutiques La Rochelle-L'Houmeau [ LRHLR] | |
| dc.contributor.author | GUIONNET, Tiphaine | |
| hal.structure.identifier | Laboratoire Ressources Halieutiques La Rochelle-L'Houmeau [ LRHLR] | |
| hal.structure.identifier | Unité Biogéochimie et Ecotoxicologie [BE] | |
| dc.contributor.author | LYPHOUT, Laura | |
| hal.structure.identifier | Physiopathologie Animale et bioThérapie du muscle et du système nerveux [PAnTher] | |
| dc.contributor.author | LEDEVIN, Mireille | |
| hal.structure.identifier | Unité Biogéochimie et Ecotoxicologie [BE] | |
| dc.contributor.author | GOUBEAU, Manon | |
| hal.structure.identifier | Environnements et Paléoenvironnements OCéaniques [EPOC] | |
| dc.contributor.author | BUDZINSKI, Hélène
ORCID: 0000-0003-1028-9154 IDREF: 070478090 | |
| hal.structure.identifier | Laboratoire Ressources Halieutiques La Rochelle-L'Houmeau [ LRHLR] | |
| dc.contributor.author | BÉGOUT, Marie-Laure | |
| hal.structure.identifier | Laboratoire de Physiologie et Génomique des Poissons [LPGP] | |
| hal.structure.identifier | Unité Biogéochimie et Ecotoxicologie [BE] | |
| hal.structure.identifier | MARine Biodiversity Exploitation and Conservation [UMR MARBEC] | |
| dc.contributor.author | COUSIN, Xavier | |
| dc.date.accessioned | 2024-04-04T12:31:19Z | |
| dc.date.available | 2024-04-04T12:31:19Z | |
| dc.date.issued | 2016-10-28 | |
| dc.identifier.issn | 2305-6304 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/194930 | |
| dc.description.abstractEn | Polycyclic aromatic hydrocarbons (PAHs) constitute a large family of organic pollutants emitted in the environment as complex mixtures, the compositions of which depend on origin. Among a wide range of physiological defects, PAHs are suspected to be involved in disruption of reproduction. In an aquatic environment, the trophic route is an important source of chronic exposure to PAHs. Here, we performed trophic exposure of zebrafish to three fractions of different origin, one pyrolytic and two petrogenic. Produced diets contained PAHs at environmental concentrations. Reproductive traits were analyzed at individual, tissue and molecular levels. Reproductive success and cumulative eggs number were disrupted after exposure to all three fractions, albeit to various extents depending on the fraction and concentrations. Histological analyses revealed ovary maturation defects after exposure to all three fractions as well as degeneration after exposure to a pyrolytic fraction. In testis, hypoplasia was observed after exposure to petrogenic fractions. Genes expression analysis in gonads has allowed us to establish common pathways such as endocrine disruption or differentiation/maturation defects. Taken altogether, these results indicate that PAHs can indeed disrupt fish reproduction and that different fractions trigger different pathways resulting in different effects. | |
| dc.description.sponsorship | Contamination et physiologie des poissons aux polluants - ANR-09-CESA-0002 | |
| dc.language.iso | en | |
| dc.publisher | MDPI | |
| dc.rights.uri | http://creativecommons.org/licenses/by/ | |
| dc.subject.en | molecular mechanisms | |
| dc.subject.en | gonad differentiation | |
| dc.subject.en | fertilization | |
| dc.subject.en | spawning success | |
| dc.subject.en | polycyclic aromatic hydrocarbons | |
| dc.subject.en | zebrafish | |
| dc.title.en | Fish Reproduction Is Disrupted upon Lifelong Exposure to Environmental PAHs Fractions Revealing Different Modes of Action | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.3390/toxics4040026 | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Toxicologie/Ecotoxicologie | |
| dc.subject.hal | Sciences de l'environnement/Biodiversité et Ecologie | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Biologie de la reproduction | |
| dc.subject.hal | Sciences du Vivant [q-bio]/Biologie animale/Zoologie des vertébrés | |
| bordeaux.journal | Toxics | en_US |
| bordeaux.page | 26 | |
| bordeaux.volume | 4 | |
| bordeaux.hal.laboratories | EPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805 | en_US |
| bordeaux.issue | 4 | |
| bordeaux.institution | Université de Bordeaux | |
| bordeaux.institution | CNRS | |
| bordeaux.peerReviewed | oui | |
| bordeaux.import.source | hal | |
| hal.identifier | hal-01425791 | |
| hal.version | 1 | |
| hal.popular | non | |
| hal.audience | Non spécifiée | |
| hal.export | false | |
| workflow.import.source | hal | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Toxics&rft.date=2016-10-28&rft.volume=4&rft.issue=4&rft.spage=26&rft.epage=26&rft.eissn=2305-6304&rft.issn=2305-6304&rft.au=VIGNET,%20Caroline&LARCHER,%20Thibaut&DAVAIL,%20Blandine&JOASSARD,%20Lucette&LE%20MENACH,%20Karyn&rft.genre=article |
