hal.structure.identifier | Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute [ICM] | |
dc.contributor.author | WELTER, Marie-Laure | |
hal.structure.identifier | Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute [ICM] | |
hal.structure.identifier | CHU Pitié-Salpêtrière [AP-HP] | |
dc.contributor.author | SCHÜPBACH, Michael | |
hal.structure.identifier | Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière [CRICM] | |
dc.contributor.author | CZERNECKI, Virginie | |
hal.structure.identifier | Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute [ICM] | |
dc.contributor.author | KARACHI, Carine | |
hal.structure.identifier | Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière [CRICM] | |
dc.contributor.author | FERNANDEZ-VIDAL, Sara | |
hal.structure.identifier | Département de Biostatistiques [Paris] | |
dc.contributor.author | GOLMARD, Jean-Louis | |
hal.structure.identifier | Dipartimento di Scienze della Terra [Cagliari] | |
dc.contributor.author | SERRA, Giulia | |
hal.structure.identifier | Transformation Intégrée de la Matière Renouvelable [TIMR] | |
dc.contributor.author | NAVARRO, Soledad | |
hal.structure.identifier | CHU Pitié-Salpêtrière [AP-HP] | |
dc.contributor.author | WELARATNE, Arlette | |
hal.structure.identifier | Institut de Mathématiques de Bordeaux [IMB] | |
dc.contributor.author | HARTMANN, Andréas | |
dc.contributor.author | MESNAGE, Valérie | |
hal.structure.identifier | CHU Pitié-Salpêtrière [AP-HP] | |
dc.contributor.author | PINEAU, Fanny | |
hal.structure.identifier | CHU Pitié-Salpêtrière [AP-HP] | |
dc.contributor.author | CORNU, Philippe | |
hal.structure.identifier | CHU Pitié-Salpêtrière [AP-HP] | |
dc.contributor.author | PIDOUX, Bernard | |
hal.structure.identifier | CIC AP-HP (pitie-Salpetriere)/inserm | |
dc.contributor.author | WORBE, Yulia | |
hal.structure.identifier | Service de neurologie [Poitiers] | |
hal.structure.identifier | Hellenic Air Force General Hospital [Athens] | |
dc.contributor.author | ZIKOS, Panayiotis | |
hal.structure.identifier | Université Pierre et Marie Curie - Paris 6 [UPMC] | |
dc.contributor.author | GRABLI, David | |
hal.structure.identifier | CHU Pitié-Salpêtrière [AP-HP] | |
hal.structure.identifier | Algorithms, models and methods for images and signals of the human brain = Algorithmes, modèles et méthodes pour les images et les signaux du cerveau humain [ICM Paris] [ARAMIS] | |
dc.contributor.author | GALANAUD, Damien | |
hal.structure.identifier | Centre de recherche sur l'espace sonore et l'environnement urbain [CRESSON] | |
dc.contributor.author | BONNET, Anne-Marie | |
hal.structure.identifier | Laboratory of Physics of Materials and Nanomaterials Applied at Environment [LaPhyMNE] | |
dc.contributor.author | BELAID, Hayat | |
hal.structure.identifier | Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute [ICM] | |
hal.structure.identifier | Algorithms, models and methods for images and signals of the human brain = Algorithmes, modèles et méthodes pour les images et les signaux du cerveau humain [ICM Paris] [ARAMIS] | |
hal.structure.identifier | CHU Pitié-Salpêtrière [AP-HP] | |
dc.contributor.author | DORMONT, Didier | |
hal.structure.identifier | Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute [ICM] | |
dc.contributor.author | VIDAILHET, Marie | |
hal.structure.identifier | Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute [ICM] | |
dc.contributor.author | MALLET, Luc | |
hal.structure.identifier | Service de neurologie [Poitiers] | |
dc.contributor.author | HOUETO, Jean-Luc | |
hal.structure.identifier | Plateforme de neuroimagerie CENIR = Center for NeuroImaging Research-Human MRI Neuroimaging core facility for clinical research [ICM Paris] [CENIR] | |
dc.contributor.author | BARDINET, Eric | |
hal.structure.identifier | Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute [ICM] | |
dc.contributor.author | YELNIK, Jerome | |
hal.structure.identifier | CHU Pitié-Salpêtrière [AP-HP] | |
dc.contributor.author | AGID, Yves | |
dc.date.accessioned | 2024-04-04T03:16:27Z | |
dc.date.available | 2024-04-04T03:16:27Z | |
dc.date.issued | 2014-04-15 | |
dc.identifier.issn | 0028-3878 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/194215 | |
dc.description.abstractEn | To further determine the causes of variable outcome from deep brain stimulation of the subthalamic nucleus (DBS-STN) in patients with Parkinson disease (PD). Data were obtained from our cohort of 309 patients with PD who underwent DBS-STN between 1996 and 2009. We examined the relationship between the 1-year motor, cognitive, and psychiatric outcomes and (1) preoperative PD clinical features, (2) MRI measures, (3) surgical procedure, and (4) locations of therapeutic contacts. Pre- and postoperative results were obtained in 262 patients with PD. The best motor outcome was obtained when stimulating contacts were located within the STN as compared with the zona incerta (64% vs 49% improvement). Eighteen percent of the patients presented a postoperative cognitive decline, which was found to be principally related to the surgical procedure. Other factors predictive of poor cognitive outcome were perioperative confusion and psychosis. Nineteen patients showed a stimulation-induced hypomania, which was related to both the form of the disease (younger age, shorter disease duration, higher levodopa responsiveness) and the ventral contact location. Postoperative depression was more frequent in patients already showing preoperative depressive and/or residual axial motor symptoms. In this homogeneous cohort of patients with PD, we showed that (1) the STN is the best target to improve motor symptoms, (2) postoperative cognitive deficit is mainly related to the surgery itself, and (3) stimulation-induced hypomania is related to a combination of both the disease characteristics and a more ventral STN location. | |
dc.language.iso | en | |
dc.publisher | American Academy of Neurology | |
dc.subject.mesh | Aged | |
dc.subject.mesh | Deep Brain Stimulation | |
dc.subject.mesh | Parkinson Disease | |
dc.subject.mesh | Postoperative Period | |
dc.subject.mesh | Subthalamic Nucleus | |
dc.subject.mesh | Treatment Outcome | |
dc.subject.mesh | Female | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Magnetic Resonance Imaging | |
dc.subject.mesh | Male | |
dc.subject.mesh | Middle Aged | |
dc.title.en | Optimal target localization for subthalamic stimulation in patients with Parkinson disease | |
dc.type | Article de revue | |
dc.identifier.doi | 10.1212/WNL.0000000000000315 | |
dc.subject.hal | Sciences de l'ingénieur [physics]/Traitement du signal et de l'image | |
dc.subject.hal | Informatique [cs]/Vision par ordinateur et reconnaissance de formes [cs.CV] | |
dc.subject.hal | Informatique [cs]/Imagerie médicale | |
dc.subject.hal | Informatique [cs]/Traitement des images | |
dc.subject.hal | Sciences du Vivant [q-bio]/Ingénierie biomédicale/Imagerie | |
dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC]/Neurobiologie | |
bordeaux.journal | Neurology | |
bordeaux.page | 1352-61 | |
bordeaux.volume | 82 | |
bordeaux.hal.laboratories | Institut de Mathématiques de Bordeaux (IMB) - UMR 5251 | * |
bordeaux.issue | 15 | |
bordeaux.institution | Université de Bordeaux | |
bordeaux.institution | Bordeaux INP | |
bordeaux.institution | CNRS | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-01251658 | |
hal.version | 1 | |
hal.popular | non | |
hal.audience | Internationale | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-01251658v1 | |
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