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On the Suitability of Elekta's Agility 160 MLC for Tracked Radiation Delivery: Closed-loop Machine Performance

hal.structure.identifierUniversity Medical Center [Utrecht] [UMCU]
dc.contributor.authorGLITZNER, M
hal.structure.identifierUniversity Medical Center [Utrecht] [UMCU]
dc.contributor.authorCRIJNS, S P M
hal.structure.identifierInstitut de Mathématiques de Bordeaux [IMB]
hal.structure.identifierUniversity Medical Center [Utrecht] [UMCU]
dc.contributor.authorDENIS DE SENNEVILLE, Baudoin
hal.structure.identifierUniversity Medical Center [Utrecht] [UMCU]
dc.contributor.authorLAGENDIJK, J
hal.structure.identifierUniversity Medical Center [Utrecht] [UMCU]
dc.contributor.authorRAAYMAKERS, B
dc.date.accessioned2024-04-04T03:09:13Z
dc.date.available2024-04-04T03:09:13Z
dc.date.issued2015
dc.identifier.issn0031-9155
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/193589
dc.description.abstractEnFor motion adaptive radiotherapy, dynamic multileaf collimator (dMLC) tracking can be employed to reduce treatment margins by steering the beam according to the organ motion. Until now, the Elekta Agility 160 MLC has hitherto not been evaluated for its tracking suitability under physiologic conditions. Both dosimetric performance and latency are key figures and need to be assessed generically, independent of the used motion sensor. In this paper, we propose to use harmonic functions directly fed to the MLC to determine its latency during continuous motion. Furthermore, a control variable is extracted from a camera system and fed to the MLC. Using this setup, film dosimetry and subsequent γ statistics are performed, evaluating the response when tracking magnetic resonance imaging (MRI)-based physiologic motion in a closed-loop. The delay attributed to the MLC itself was shown to be a minor contributor to the overall feedback chain as compared to the impact of imaging components such as MRI sequences. Delay showed a linear phase behaviour of the MLC employed in continuously dynamic applications, which enables a general MLC-characterization. Using the exemplary feedback chain, dosimetry showed a vast increase in pass rate employing γ statistics. In this early stage, the tracking performance of the Agility using the test bench yielded promising results, making the technique eligible for the translation to tracking using clinical imaging modalities.
dc.language.isoen
dc.publisherIOP Publishing
dc.subject.enlinear-phase
dc.subject.enband-limited
dc.subject.endelay analysis
dc.subject.ensystem response
dc.subject.entracking
dc.subject.enMLC
dc.subject.enphysiologic motion
dc.title.enOn the Suitability of Elekta's Agility 160 MLC for Tracked Radiation Delivery: Closed-loop Machine Performance
dc.typeArticle de revue
dc.identifier.doi10.1088/0031-9155/60/5/2005/meta
dc.subject.halSciences de l'ingénieur [physics]/Traitement du signal et de l'image
dc.subject.halSciences du Vivant [q-bio]/Ingénierie biomédicale/Médecine nucléaire
bordeaux.journalPhysics in Medicine and Biology
bordeaux.page2005-2017
bordeaux.volume60
bordeaux.hal.laboratoriesInstitut de Mathématiques de Bordeaux (IMB) - UMR 5251*
bordeaux.issue5
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierhal-01578210
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-01578210v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Physics%20in%20Medicine%20and%20Biology&rft.date=2015&rft.volume=60&rft.issue=5&rft.spage=2005-2017&rft.epage=2005-2017&rft.eissn=0031-9155&rft.issn=0031-9155&rft.au=GLITZNER,%20M&CRIJNS,%20S%20P%20M&DENIS%20DE%20SENNEVILLE,%20Baudoin&LAGENDIJK,%20J&RAAYMAKERS,%20B&rft.genre=article


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