Three-Dimensional Measurement Of hepatocellular carcinoma Ablation Zones And Margins For Predicting Local Tumor Progression
hal.structure.identifier | Hôpital Saint-André | |
dc.contributor.author | HOCQUELET, Arnaud | |
hal.structure.identifier | Hôpital Saint-André | |
dc.contributor.author | TRILLAUD, Hervé | |
hal.structure.identifier | Service d'imagerie diagnostique et interventionelle | |
dc.contributor.author | FRULIO, Nora | |
hal.structure.identifier | Hôpital Saint-André | |
dc.contributor.author | PAPADOPOULOS, Panteleimon | |
hal.structure.identifier | Hôpital Saint-André | |
dc.contributor.author | BALAGEAS, P. | |
hal.structure.identifier | Hôpital Saint-André | |
dc.contributor.author | SALUT, C. | |
hal.structure.identifier | Hôpital Saint-André | |
dc.contributor.author | MEYER, Marie | |
hal.structure.identifier | Hôpital Saint-André | |
dc.contributor.author | BLANC, Jean-Frédéric | |
hal.structure.identifier | Hôpital Haut-Lévêque [CHU Bordeaux] | |
dc.contributor.author | MONTAUDON, Michel | |
hal.structure.identifier | Institut de Mathématiques de Bordeaux [IMB] | |
dc.contributor.author | DENIS DE SENNEVILLE, Baudouin | |
dc.date.accessioned | 2024-04-04T03:07:02Z | |
dc.date.available | 2024-04-04T03:07:02Z | |
dc.date.issued | 2016 | |
dc.identifier.issn | 1051-0443 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/193398 | |
dc.description.abstractEn | Purpose: To propose a postprocessing technique that measures tumor surface with insufficient ablative margins (r 5 mm) on magnetic resonance (MR) imaging to predict local tumor progression (LTP) following radiofrequency (RF) ablation.Materials and Methods: A diagnostic method is proposed based on measurement of tumor surface with a margin r 5 mm on MR imaging. The postprocessing technique includes fully automatic registration of pre-and post–RF ablation MR imaging, a semiautomatic segmentation of pre–RF ablation tumor and post–RF ablation volume, and a subsequent calculation of the three-dimensional exposed tumor surface area. The ability to use this surface margin r 5 mm to predict local recurrence at 2 years was then tested on 16 patients with cirrhosis who were treated by RF ablation with a margin r 5 mm in 2012: eight with LTP matched according to tumor size and number and α-fetoprotein level versus eight without local recurrence. Results: The error of estimated tumor surface with a margin r 5 mm was less than 12%.Results of a log-rank test showed that patients with a tumor surface area 4 425 mm 2 had a 2-year LTP rate of 77.5%, compared with 25% for patients with a tumor surface area r 425 mm 2 (P ¼ .018).Conclusions: This proof-of-concept study proposes an accurate and reliable postprocessing technique to estimate tumor surface with insufficient ablative margins, and underscores the potential usefulness of tumor surface with a margin r 5 mm to stratify patients with HCC treated by RF ablation according to their risk of LTP. | |
dc.language.iso | en | |
dc.publisher | Elsevier | |
dc.title.en | Three-Dimensional Measurement Of hepatocellular carcinoma Ablation Zones And Margins For Predicting Local Tumor Progression | |
dc.type | Article de revue | |
dc.identifier.doi | 10.1016/j.jvir.2016.02.031 | |
dc.subject.hal | Sciences du Vivant [q-bio]/Ingénierie biomédicale/Imagerie | |
dc.subject.hal | Sciences de l'ingénieur [physics]/Traitement du signal et de l'image | |
dc.subject.hal | Sciences du Vivant [q-bio]/Cancer | |
bordeaux.journal | JVIR: Journal of Vascular and Interventional Radiology | |
bordeaux.page | 1038-1045.e2 | |
bordeaux.volume | 27 | |
bordeaux.hal.laboratories | Institut de Mathématiques de Bordeaux (IMB) - UMR 5251 | * |
bordeaux.issue | 7 | |
bordeaux.institution | Université de Bordeaux | |
bordeaux.institution | Bordeaux INP | |
bordeaux.institution | CNRS | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-01312564 | |
hal.version | 1 | |
hal.popular | non | |
hal.audience | Internationale | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-01312564v1 | |
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