Maximal conductances ionic parameters estimation in cardiac electrophysiology multiscale modelling
hal.structure.identifier | Laboratoire de Modélisation Mathématique et Numérique dans les Sciences de l'Ingénieur [Tunis] [LR-LAMSIN-ENIT] | |
dc.contributor.author | ABIDI, Yassine | |
hal.structure.identifier | IHU-LIRYC | |
dc.contributor.author | BOUYSSIER, Julien | |
hal.structure.identifier | Laboratoire de Modélisation Mathématique et Numérique dans les Sciences de l'Ingénieur [Tunis] [LR-LAMSIN-ENIT] | |
dc.contributor.author | MAHJOUB, Moncef | |
hal.structure.identifier | Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN] | |
dc.contributor.author | ZEMZEMI, Nejib | |
dc.contributor.editor | Yves Coudière | |
dc.contributor.editor | Valéry Ozenne | |
dc.contributor.editor | Edward Vigmond | |
dc.contributor.editor | Nejib Zemzemi | |
dc.date.accessioned | 2024-04-04T03:00:46Z | |
dc.date.available | 2024-04-04T03:00:46Z | |
dc.date.issued | 2019-05-30 | |
dc.date.conference | 2019-06-06 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/192846 | |
dc.description.abstractEn | In this work, we present an optimal control formulation for the bidomain model in order to estimate maximal conductances parameters in the physiological ionic model. We consider a general Hodgkin-Huxley formalism to describe the ionic exchanges at the microcopic level. We consider the parameters as control variables to minimize the mismatch between the measured and the computed potentials under the constraint of the bidomain system. The solution of the optimization problem is based on a gradient descent method, where the gradient is obtained by solving an adjoint problem. We show through some numerical examples the capability of this approach to estimate the values of sodium, calcium and potassium ion channels conductances in the Luo Rudy phase I model. | |
dc.description.sponsorship | L'Institut de Rythmologie et modélisation Cardiaque - ANR-10-IAHU-0004 | |
dc.language.iso | en | |
dc.publisher | Springer | |
dc.subject.en | Bidomain model | |
dc.subject.en | Physiological ionic model | |
dc.subject.en | First order optimality conditions | |
dc.subject.en | Maximal conductance ionic parameters | |
dc.subject.en | Cardiac electrophysiology | |
dc.subject.en | Parameters estimation | |
dc.subject.en | Optimal control with PDE constraints | |
dc.title.en | Maximal conductances ionic parameters estimation in cardiac electrophysiology multiscale modelling | |
dc.type | Communication dans un congrès | |
dc.identifier.doi | 10.1007/978-3-030-21949-9 | |
dc.subject.hal | Sciences du Vivant [q-bio]/Médecine humaine et pathologie/Cardiologie et système cardiovasculaire | |
dc.subject.hal | Informatique [cs]/Modélisation et simulation | |
dc.subject.hal | Science non linéaire [physics] | |
dc.subject.hal | Mathématiques [math]/Equations aux dérivées partielles [math.AP] | |
dc.subject.hal | Mathématiques [math]/Optimisation et contrôle [math.OC] | |
bordeaux.page | 131-138 | |
bordeaux.volume | 11504 | |
bordeaux.hal.laboratories | Institut de Mathématiques de Bordeaux (IMB) - UMR 5251 | * |
bordeaux.institution | Université de Bordeaux | |
bordeaux.institution | Bordeaux INP | |
bordeaux.institution | CNRS | |
bordeaux.conference.title | FIMH 2019 - 10th International Conference Functionnal Imaging and Modeling of the Heart | |
bordeaux.country | FR | |
bordeaux.conference.city | Bordeaux | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-02154074 | |
hal.version | 1 | |
hal.invited | non | |
hal.proceedings | oui | |
hal.conference.organizer | Y. Coudière, V. Ozenne, E. Vigmond and N. Zemzemi | |
hal.conference.end | 2019-06-08 | |
hal.popular | non | |
hal.audience | Internationale | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-02154074v1 | |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.date=2019-05-30&rft.volume=11504&rft.spage=131-138&rft.epage=131-138&rft.au=ABIDI,%20Yassine&BOUYSSIER,%20Julien&MAHJOUB,%20Moncef&ZEMZEMI,%20Nejib&rft.genre=unknown |
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