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Neural support of manual preference revealed by BOLD variations during right and left finger-tapping in a sample of 287 healthy adults balanced for handedness

hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorTZOURIO MAZOYER, Nathalie
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
hal.structure.identifierInstitut de Mathématiques de Bordeaux [IMB]
hal.structure.identifierQuality control and dynamic reliability [CQFD]
dc.contributor.authorLABACHE, Loic
hal.structure.identifierGroupe d'imagerie neurofonctionnelle [GIN]
dc.contributor.authorZAGO, Laure
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorHESLING, Isabelle
hal.structure.identifierInstitut des Maladies Neurodégénératives [Bordeaux] [IMN]
dc.contributor.authorMAZOYER, Bernard
dc.date.accessioned2024-04-04T02:45:18Z
dc.date.available2024-04-04T02:45:18Z
dc.date.issued2021
dc.identifier.issn1357-650X
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/191454
dc.description.abstractEnWe have identified the brain areas involved in Manual Preference (MP) in 143 left-handers (LH) and 144 right-handers (RH). First, we selected the pairs of homotopic regions of interest (hROIs) of the AICHA atlas with significant contralateral activation and asymmetry during the right hand and the left hand Finger-Tapping (FT) both in RH and LH. Thirteen hROIs were selected, including the primary and secondary sensorimotor and premotor cortices, thalamus, dorsal putamen, and cerebellar lobule IV. In both groups, contralateral activations and ipsilateral deactivations were seen, with stronger asymmetries when the preferred hand was used. Comparing with different models for the prediction of MP, we found that the differences in activity during preferred hand minus non-preferred hand movement in 11 contralateral and/or ipsilateral hROIS were best at explaining handedness distribution. Two different mechanisms were identified: 1. Stronger contralateral activity of cortical and cerebellar motor areas during right hand movement, seen in both groups but modulated by handedness; 2. Stronger deactivation in ipsilateral areas during dominant hand movement in both groups, LH here mirroring RH. The present study thus demonstrates that handedness neural support is complex and not simply based on a mirrored organization of hand motor areas.
dc.language.isoen
dc.publisherTaylor & Francis
dc.subject.enHandedness
dc.subject.enfMRI
dc.subject.enFinger tapping
dc.subject.enDeactivation
dc.subject.enAtlas
dc.title.enNeural support of manual preference revealed by BOLD variations during right and left finger-tapping in a sample of 287 healthy adults balanced for handedness
dc.typeArticle de revue
dc.identifier.doi10.1080/1357650X.2020.1862142
dc.subject.halSciences cognitives/Neurosciences
bordeaux.journalLaterality
bordeaux.page398-420
bordeaux.volume26
bordeaux.hal.laboratoriesInstitut de Mathématiques de Bordeaux (IMB) - UMR 5251*
bordeaux.issue4
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionBordeaux INP
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierhal-03101306
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-03101306v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Laterality&rft.date=2021&rft.volume=26&rft.issue=4&rft.spage=398-420&rft.epage=398-420&rft.eissn=1357-650X&rft.issn=1357-650X&rft.au=TZOURIO%20MAZOYER,%20Nathalie&LABACHE,%20Loic&ZAGO,%20Laure&HESLING,%20Isabelle&MAZOYER,%20Bernard&rft.genre=article


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