Uncertainty Quantification of the Effects of Segmentation Variability in ECGI
hal.structure.identifier | University of Utah | |
dc.contributor.author | TATE, Jess | |
hal.structure.identifier | University of Utah | |
dc.contributor.author | GOOD, Wilson | |
hal.structure.identifier | Modélisation et calculs pour l'électrophysiologie cardiaque [CARMEN] | |
dc.contributor.author | ZEMZEMI, Nejib | |
hal.structure.identifier | Utrecht Brain Center [UMC] | |
dc.contributor.author | BOONSTRA, Machteld | |
hal.structure.identifier | Utrecht Brain Center [UMC] | |
dc.contributor.author | VAN DAM, Peter | |
hal.structure.identifier | Northeastern University [Boston] | |
dc.contributor.author | BROOKS, Dana | |
hal.structure.identifier | University of Utah | |
dc.contributor.author | NARAYAN, Akil | |
hal.structure.identifier | University of Utah | |
dc.contributor.author | MACLEOD, Rob | |
dc.contributor.editor | Daniel B. Ennis | |
dc.contributor.editor | Luigi E. Perotti | |
dc.contributor.editor | Vicky Y. Wang | |
dc.date.accessioned | 2024-04-04T02:40:15Z | |
dc.date.available | 2024-04-04T02:40:15Z | |
dc.date.issued | 2021-06-18 | |
dc.date.conference | 2021-06-21 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/191049 | |
dc.description.abstractEn | Despite advances in many of the techniques used in Electrocardiographic Imaging (ECGI), uncertainty remains insufficiently quantified for many aspects of the pipeline. The effect of geometric uncertainty, particularly due to segmentation variability, may be the least explored to date. We use statistical shape modeling and uncertainty quantification (UQ) to compute the effect of segmentation variability on ECGI solutions. The shape model was made with Shapeworks from nine segmentations of the same patient and incorporated into an ECGI pipeline. We computed uncertainty of the pericardial potentials and local activation times (LATs) using polynomial chaos expansion (PCE) implemented in UncertainSCI. Uncertainty in pericardial potentials from segmentation variation mirrored areas of high variability in the shape model, near the base of the heart and the right ventricular outflow tract, and that ECGI was less sensitive to uncertainty in the posterior region of the heart. Subsequently LAT calculations could vary dramatically due to segmentation variability, with a standard deviation as high as 126ms, yet mainly in regions with low conduction velocity. Our shape modeling and UQ pipeline presented possible uncertainty in ECGI due to segmentation variability and can be used by researchers to reduce said uncertainty or mitigate its effects. The demonstrated use of statistical shape modeling and UQ can also be extended to other types of modeling pipelines. | |
dc.language.iso | en | |
dc.publisher | Springer International Publishing | |
dc.source.title | Lecture Notes in Computer Science | |
dc.subject.en | Electrocardiographic Imaging | |
dc.subject.en | Shape Analysis | |
dc.subject.en | Uncertainty Quantification | |
dc.title.en | Uncertainty Quantification of the Effects of Segmentation Variability in ECGI | |
dc.type | Communication dans un congrès | |
dc.identifier.doi | 10.1007/978-3-030-78710-3_49 | |
dc.subject.hal | Informatique [cs]/Modélisation et simulation | |
bordeaux.page | 515-522 | |
bordeaux.volume | LNCS-12738 | |
bordeaux.hal.laboratories | Institut de Mathématiques de Bordeaux (IMB) - UMR 5251 | * |
bordeaux.institution | Université de Bordeaux | |
bordeaux.institution | Bordeaux INP | |
bordeaux.institution | CNRS | |
bordeaux.conference.title | FIMH 2021 - 11th International Conference on Functional Imaging and Modeling of the Heart | |
bordeaux.country | US | |
bordeaux.title.proceeding | Lecture Notes in Computer Science | |
bordeaux.conference.city | Stanford | |
bordeaux.peerReviewed | oui | |
hal.identifier | hal-03805280 | |
hal.version | 1 | |
hal.invited | non | |
hal.proceedings | oui | |
hal.conference.end | 2021-06-25 | |
hal.popular | non | |
hal.audience | Internationale | |
hal.origin.link | https://hal.archives-ouvertes.fr//hal-03805280v1 | |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.btitle=Lecture%20Notes%20in%20Computer%20Science&rft.date=2021-06-18&rft.volume=LNCS-12738&rft.spage=515-522&rft.epage=515-522&rft.au=TATE,%20Jess&GOOD,%20Wilson&ZEMZEMI,%20Nejib&BOONSTRA,%20Machteld&VAN%20DAM,%20Peter&rft.genre=unknown |
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