Brain artery diameters and risk of dementia and stroke
dc.rights.license | open | en_US |
dc.contributor.author | MELGAREJO, Jesus D | |
dc.contributor.author | GUREL, Kursat | |
dc.contributor.author | COMPTON, Cassidy Rose | |
dc.contributor.author | LIU, Minghua | |
dc.contributor.author | GUZMAN, Vanessa | |
dc.contributor.author | ASSURAS, Stephanie | |
dc.contributor.author | LEVIN, Bonnie E | |
dc.contributor.author | ELKIND, Mitchell S V | |
dc.contributor.author | IKRAM, M Kamran | |
dc.contributor.author | KAVOUSI, Maryam | |
dc.contributor.author | IKRAM, M Arfan | |
dc.contributor.author | WRIGHT, Clinton | |
dc.contributor.author | CRIVELLO, Fabrice | |
dc.contributor.author | LAURENT, Alexandre | |
hal.structure.identifier | Bordeaux population health [BPH] | |
dc.contributor.author | TZOURIO, Christophe
IDREF: 69829209 | |
dc.contributor.author | VERNOOIJ, Meike W | |
dc.contributor.author | RUNDEK, Tatjana | |
dc.contributor.author | ZHANG, Zhen-Yu | |
dc.contributor.author | BOS, Daniel | |
dc.contributor.author | GUTIERREZ, Jose | |
dc.date.accessioned | 2024-03-14T14:37:22Z | |
dc.date.available | 2024-03-14T14:37:22Z | |
dc.date.issued | 2024-02-08 | |
dc.identifier.issn | 1552-5279 (Electronic) 1552-5260 (Linking) | en_US |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/188800 | |
dc.description.abstractEn | INTRODUCTION: We tested the association of brain artery diameters with dementia and stroke risk in three distinct population-based studies using conventional T2-weighted brain magnetic resonance imaging (MRI) images. METHODS: We included 8420 adults > 40 years old from three longitudinal population-based studies with brain MRI scans. We estimated and meta-analyzed the hazard ratios (HRs) of the brain and carotids and basilar diameters associated with dementia and stroke. RESULT: Overall and carotid artery diameters > 95th percentile increased the risk for dementia by 1.74 (95% confidence interval [CI], 1.13-2.68) and 1.48 (95% CI, 1.12-1.96) fold, respectively. For stroke, meta-analyses yielded HRs of 1.59 (95% CI, 1.04-2.42) for overall arteries and 2.11 (95% CI, 1.45-3.08) for basilar artery diameters > 95th percentile. DISCUSSION: Individuals with dilated brain arteries are at higher risk for dementia and stroke, across distinct populations. Our findings underline the potential value of T2-weighted brain MRI-based brain diameter assessment in estimating the risk of dementia and stroke. | |
dc.language.iso | EN | en_US |
dc.subject.en | Brain artery diameter | |
dc.subject.en | Dementia | |
dc.subject.en | Magnetic resonance imaging | |
dc.subject.en | Population-based science | |
dc.subject.en | Stroke | |
dc.title.en | Brain artery diameters and risk of dementia and stroke | |
dc.title.alternative | Alzheimers Dement | en_US |
dc.type | Article de revue | en_US |
dc.identifier.doi | 10.1002/alz.13712 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
dc.identifier.pubmed | 38332543 | en_US |
bordeaux.journal | Alzheimer’s and Dementia | en_US |
bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | INSERM | en_US |
bordeaux.team | HEALTHY_BPH | en_US |
bordeaux.peerReviewed | oui | en_US |
bordeaux.inpress | non | en_US |
hal.identifier | hal-04505022 | |
hal.version | 1 | |
hal.date.transferred | 2024-03-14T14:37:25Z | |
hal.popular | non | en_US |
hal.audience | Internationale | en_US |
hal.export | true | |
dc.rights.cc | Pas de Licence CC | en_US |
bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Alzheimer%E2%80%99s%20and%20Dementia&rft.date=2024-02-08&rft.eissn=1552-5279%20(Electronic)%201552-5260%20(Linking)&rft.issn=1552-5279%20(Electronic)%201552-5260%20(Linking)&rft.au=MELGAREJO,%20Jesus%20D&GUREL,%20Kursat&COMPTON,%20Cassidy%20Rose&LIU,%20Minghua&GUZMAN,%20Vanessa&rft.genre=article |
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