Afficher la notice abrégée

Retrotransposon methylation and activity in wild fish (A. anguilla): A matter of size

dc.rights.licenseopenen_US
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorPIERRON, Fabien
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorDAFFE, Guillemine
hal.structure.identifierEcosystèmes aquatiques et changements globaux [UR EABX]
dc.contributor.authorLAMBERT, Patrick
hal.structure.identifierCentre Eau Terre Environnement [Québec] [INRS - ETE]
dc.contributor.authorCOUTURE, Patrice
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorBAUDRIMONT, Magalie
IDREF: 105696722
dc.date.accessioned2024-01-30T09:57:11Z
dc.date.available2024-01-30T09:57:11Z
dc.date.issued2019-02
dc.identifier.issn0269-7491en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/187631
dc.description.abstractEnUnderstanding how organisms cope with global change is a major question in many fields of biology. Mainly, understanding the molecular mechanisms supporting rapid phenotypic changes of organisms in response to stress and linking stress-induced molecular events to adaptive or adverse outcomes at the individual or population levels remain a major challenge in evolutionary biology, ecology or ecotoxicology. In this view, the present study aimed to test (i) whether environmental factors, especially pollutants, can trigger changes in the activity of retrotransposons (RTs) in wild fish and (ii) if changes in RT DNA methylation or transcription levels can be linked to modifications at the individual level. RTs are genetic elements that have the ability to replicate and integrate elsewhere in the genome. Although RTs are mainly quiescent during normal development, they can be experimentally activated under life-threatening conditions, affecting the fitness of their host. Wild eels were collected in four sampling sites presenting differing levels of contamination. The methylation level and the transcriptional activity of two RTs and two genes involved in development and cell differentiation were analyzed in fish liver in addition to the determination of fish contaminants levels and diverse growth and morphometric indices. An up-regulation of RTs associated to lower methylation levels and lower growth indices were observed in highly contaminated fish. Our results suggest that RT activation in fish experiencing stress conditions could have both detrimental and beneficial implications, affecting fish growth but promoting resistance to environmental stressors such as pollutants. Retrotransposons could represent interesting environment-sensitive molecular markers allowing to link stress-induced molecular events to adverse outcomes at higher levels.
dc.description.sponsorshipEffets transgénérationnels des polluants chez les poissons: l'épigénétique et son implication en écotoxicologie - ANR-16-CE34-0008en_US
dc.language.isoENen_US
dc.subject.enMETHYLATION
dc.title.enRetrotransposon methylation and activity in wild fish (A. anguilla): A matter of size
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.envpol.2018.11.014en_US
dc.subject.halSciences du Vivant [q-bio]/Toxicologie/Ecotoxicologieen_US
dc.subject.halSciences de l'environnementen_US
dc.subject.halSciences de l'environnement/Biodiversité et Ecologieen_US
dc.subject.halSciences du Vivant [q-bio]/Biochimie, Biologie Moléculaireen_US
bordeaux.journalEnvironmental Pollutionen_US
bordeaux.page494-503en_US
bordeaux.volume245en_US
bordeaux.hal.laboratoriesEPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.teamEAen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-02354020
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.subject.esRETROTRANSPOSON
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Environmental%20Pollution&rft.date=2019-02&rft.volume=245&rft.spage=494-503&rft.epage=494-503&rft.eissn=0269-7491&rft.issn=0269-7491&rft.au=PIERRON,%20Fabien&DAFFE,%20Guillemine&LAMBERT,%20Patrick&COUTURE,%20Patrice&BAUDRIMONT,%20Magalie&rft.genre=article


Fichier(s) constituant ce document

FichiersTailleFormatVue

Il n'y a pas de fichiers associés à ce document.

Ce document figure dans la(les) collection(s) suivante(s)

Afficher la notice abrégée