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Adverse effects induced by chronic gamma irradiation in progeny of adult fish not affecting parental reproductive performance

dc.rights.licenseopenen_US
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorGUIRANDY, Noémie
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorGAGNAIRE, Béatrice
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorFRELON, Sandrine
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorMUNCH, Thomas
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorDUBOURG, Nicolas
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorCAMILLERI, Virginie
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorCAVALIE, Isabelle
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorFLORIANI, Magali
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorARCANJO, Caroline
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorMURAT EL HOUDIGUI, Sophia
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorARMANT, Olivier
hal.structure.identifierLaboratoire de micro-irradiation, de métrologie et de dosimétrie neutrons [IRSN/PSE-SANTE/SDOS/LMDN]
dc.contributor.authorADAM‐GUILLERMIN, Christelle
hal.structure.identifierEnvironnements et Paléoenvironnements OCéaniques [EPOC]
dc.contributor.authorGONZALEZ, Patrice
hal.structure.identifierLaboratoire d'écotoxicologie des radionucléides [IRSN/PSE-ENV/SRTE/LECO]
dc.contributor.authorSIMON, Olivier
dc.date.accessioned2024-01-24T10:04:38Z
dc.date.available2024-01-24T10:04:38Z
dc.date.issued2019
dc.identifier.issn0730-7268en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/187469
dc.description.abstractEnMultigenerational studies became of great interest in ecotoxicology since the consequence of parental exposure on offspring generations has been established in situ or in laboratory conditions. This study mainly examined chronic effects of external Cs-137 gamma irradiation exposure at 4 dose rates (control, 0.5, 5 and 50 mGy h-1) on adult zebrafish (F0) exposed for 10 days and its progeny (F1) exposed for 4 days. The main investigated endpoints included parental reproductive performance, embryo-larval survival, DNA alterations and ROS production in F0 and F1. No effects on reproductive success, fecundity or egg fertilization rate were observed. However, drastic effects were observed on F1 at the highest dose rate, resulting in a mortality of 100%. The drastic effects were also observed when the progeny was not irradiated. We demonstrate that the sensitivity of the embryos was mainly due to parental irradiation. Moreover, these drastic effects induced by adult irradiation disappeared over time when 10 d- irradiated adults were placed in a non-irradiated condition. DNA alterations in larvae were observed for the three dose rates, with an increase of ROS production was also shown for the two lowest dose rates. This study improves our understanding of the consequences of multigenerational exposure conditions. Furthermore, it incentivizes us to take into account transmitted generational effects in ecological risk assessments.
dc.language.isoENen_US
dc.subject.enreproduction
dc.subject.enirradiation exposure
dc.subject.enzebrafish
dc.subject.enrisk assessment
dc.title.enAdverse effects induced by chronic gamma irradiation in progeny of adult fish not affecting parental reproductive performance
dc.typeArticle de revueen_US
dc.identifier.doi10.1002/etc.4562en_US
dc.subject.halSciences du Vivant [q-bio]/Toxicologie/Ecotoxicologieen_US
dc.subject.halSciences du Vivant [q-bio]/Ecologie, Environnement/Santéen_US
bordeaux.journalEnvironmental Toxicology and Chemistryen_US
bordeaux.page2556-2567en_US
bordeaux.volume38en_US
bordeaux.hal.laboratoriesEPOC : Environnements et Paléoenvironnements Océaniques et Continentaux - UMR 5805en_US
bordeaux.issue11en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.teamEAen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-02324157
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Environmental%20Toxicology%20and%20Chemistry&rft.date=2019&rft.volume=38&rft.issue=11&rft.spage=2556-2567&rft.epage=2556-2567&rft.eissn=0730-7268&rft.issn=0730-7268&rft.au=GUIRANDY,%20No%C3%A9mie&GAGNAIRE,%20B%C3%A9atrice&FRELON,%20Sandrine&MUNCH,%20Thomas&DUBOURG,%20Nicolas&rft.genre=article


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