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Gray matter characteristics associated with trait anxiety in older adults are moderated by depression

dc.rights.licenseopenen_US
dc.contributor.authorPOTVIN, Olivier
hal.structure.identifierInstitut de Neurosciences cognitives et intégratives d'Aquitaine [INCIA]
dc.contributor.authorCATHELINE, Gwénaëlle
hal.structure.identifierInstitut de Neurosciences cognitives et intégratives d'Aquitaine [INCIA]
dc.contributor.authorBERNARD, Charlotte
hal.structure.identifierEpidémiologie et Biostatistique [Bordeaux]
dc.contributor.authorMEILLON, Celine
ORCID: 0000-0001-7891-9648
hal.structure.identifierLaboratoire de psychologie:Santé et qualité de vie
dc.contributor.authorBERGUA, Valerie
ORCID: 0000-0002-2232-1812
IDREF: 09428895X
hal.structure.identifierInstitut de Neurosciences cognitives et intégratives d'Aquitaine [INCIA]
dc.contributor.authorALLARD, Michèle
hal.structure.identifierEpidémiologie et Biostatistique [Bordeaux]
dc.contributor.authorDARTIGUES, Jean-Francois
ORCID: 0000-0001-9482-5529
IDREF: 058586105
dc.contributor.authorCHAUVEAU, Nicolas
dc.contributor.authorCELSIS, Pierre
dc.contributor.authorAMIEVA, Hélène
dc.date.accessioned2023-12-15T13:25:02Z
dc.date.available2023-12-15T13:25:02Z
dc.date.issued2015
dc.identifier.issn1741-203Xen_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/186639
dc.description.abstractEnBACKGROUND: Structural gray matter characteristics of anxiety remain unclear. The aim of this study was to assess the influence of current depressive symptoms and history of depression on the gray matter characteristics of trait anxiety. METHODS: Structural magnetic resonance imaging (MRI) data from 393 individuals aged 65 years or older were used. Regions of interest (ROIs) included the amygdala, anterior cingulate cortex (ACC), insula, orbitofrontal cortex (OFC), and temporal cortex. Trait anxiety was measured by the State-Trait Anxiety Inventory (STAI). Depression and depressive symptoms were measured using DSM-IV criteria and the Center for Epidemiological Studies Depression Scale (CESD). RESULTS: After adjustments for sociodemographics and health-related variables, anxiety had a significant influence on the gray matter characteristics in all cortical ROIs. First, in participants without depression antecedents, higher trait anxiety was associated with a larger cortical thickness in all cortical ROIs. Second, in participants with a previous history of depression, higher trait anxiety was associated with a smaller cortical thickness in all cortical ROIs. CONCLUSIONS: These results suggest that anxiety is related to cortical thickness differently in healthy older adults and in older adults with psychiatric antecedents. Anxiety associated with thinner cortical areas could reflect symptoms of a specific type of depression or a vulnerability to develop depression.
dc.language.isoENen_US
dc.title.enGray matter characteristics associated with trait anxiety in older adults are moderated by depression
dc.typeArticle de revueen_US
dc.identifier.doi10.1017/S1041610215000836en_US
dc.subject.halSciences du Vivant [q-bio]/Santé publique et épidémiologieen_US
bordeaux.journalInternational Psychogeriatricsen_US
bordeaux.page1813--1824en_US
bordeaux.volume27en_US
bordeaux.hal.laboratoriesAnciens laboratoires de l'Université de Bordeauxen_US
bordeaux.issue11en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-04345515
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=International%20Psychogeriatrics&rft.date=2015&rft.volume=27&rft.issue=11&rft.spage=1813--1824&rft.epage=1813--1824&rft.eissn=1741-203X&rft.issn=1741-203X&rft.au=POTVIN,%20Olivier&CATHELINE,%20Gw%C3%A9na%C3%ABlle&BERNARD,%20Charlotte&MEILLON,%20Celine&BERGUA,%20Valerie&rft.genre=article


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