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dc.rights.licenseopenen_US
hal.structure.identifierPolska Akademia Nauk = Polish Academy of Sciences = Académie polonaise des sciences [PAN]
hal.structure.identifierUniversity of Warsaw [UW]
dc.contributor.authorBLINOWSKA, Katarzyna
hal.structure.identifierUniversity of Warsaw [UW]
dc.contributor.authorKAMIŃSKI, Maciej
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorMACREZ, Nathalie
IDREF: 096661445
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorMARIGHETTO, Aline
hal.structure.identifierNeurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB]
dc.contributor.authorMEYRAND, Pierre
hal.structure.identifierPolska Akademia Nauk = Polish Academy of Sciences = Académie polonaise des sciences [PAN]
dc.contributor.authorBEM, Tiaza
dc.date.accessioned2023-12-04T15:37:34Z
dc.date.available2023-12-04T15:37:34Z
dc.date.issued2022-12-26
dc.identifier.issn2045-2322en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/186347
dc.description.abstractEnAbstract Slow gamma oscillations (20–50 Hz) have been suggested to coordinate information transfer between brain structures involved in memory formation. Whereas the involvement of slow gamma in memory processing was studied by means of correlation between the gamma power and the occurrence of a given event (sharp wave ripples (SWRs), cortical transients), our approach consists of the analysis of the transmission of slow gamma itself. We use the method based on Granger causality principle—direct Directed Transfer Function, which allows to determine directed propagation of brain activity, including bidirectional flows. Four cortical sites along with CA1 ipsi- and contralateral were recorded in behaving wild-type and APP/PS1 mice before and after learning session of a spatial memory task. During slow wave sleep propagation of slow gamma was bidirectional, forming multiple loops of interaction which involved both CA1 and some of cortical sites. In episodes coincident with SWRs the number and strength of connectivity pathways increased in both groups compared to episodes without SWRs. The effect of learning was expressed only in APP/PS1 mice and consisted in strengthening of the slow gamma transmission from hippocampus to cortex as well as between both CA1 which may serve more efficient transmission of information from impaired CA1.
dc.language.isoENen_US
dc.rightsAttribution 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/us/*
dc.subject.enAnimals
dc.subject.enHippocampus / metabolism
dc.subject.enMice
dc.subject.enSleep
dc.subject.enSlow-Wave
dc.subject.enSpatial Memory
dc.title.enEffect of learning on slow gamma propagation between hippocampus and cortex in the wild-type and AD mice
dc.title.alternativeSci Repen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1038/s41598-022-26754-2en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]/Neurobiologieen_US
dc.identifier.pubmed36572725en_US
bordeaux.journalScientific Reportsen_US
bordeaux.page22343en_US
bordeaux.volume12en_US
bordeaux.hal.laboratoriesNeurocentre Magendie - U1215en_US
bordeaux.issue1en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINSERMen_US
bordeaux.teamPhysiopathologie de la mémoire déclarativeen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-03926373
hal.version1
hal.popularnonen_US
hal.audienceInternationaleen_US
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccCC BYen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Scientific%20Reports&rft.date=2022-12-26&rft.volume=12&rft.issue=1&rft.spage=22343&rft.epage=22343&rft.eissn=2045-2322&rft.issn=2045-2322&rft.au=BLINOWSKA,%20Katarzyna&KAMI%C5%83SKI,%20Maciej&MACREZ,%20Nathalie&MARIGHETTO,%20Aline&MEYRAND,%20Pierre&rft.genre=article


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