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Relationships between neuropsychological performance, insight, medication adherence, and social metacognition in schizophrenia
dc.rights.license | open | en_US |
hal.structure.identifier | Fondation FondaMental [Créteil] | |
hal.structure.identifier | Centre de recherche en épidémiologie et santé des populations [CESP] | |
dc.contributor.author | ROUX, Paul | |
dc.contributor.author | FAIVRE, Nathan | |
hal.structure.identifier | Fondation FondaMental [Créteil] | |
hal.structure.identifier | Centre de recherche en épidémiologie et santé des populations [CESP] | |
dc.contributor.author | URBACH, Mathieu | |
hal.structure.identifier | Fondation FondaMental [Créteil] | |
hal.structure.identifier | Nutrition et Neurobiologie intégrée [NutriNeuro] | |
dc.contributor.author | AOUIZERATE, Bruno
IDREF: 069471851 | |
hal.structure.identifier | Fondation FondaMental [Créteil] | |
hal.structure.identifier | IMRB - "Neuropsychiatrie translationnelle" [Créteil] [U955 Inserm - UPEC] | |
dc.contributor.author | BRUNEL, Lore | |
dc.contributor.author | CAPDEVIELLE, Delphine | |
dc.contributor.author | CHEREAU, Isabelle | |
hal.structure.identifier | Fondation FondaMental [Créteil] | |
hal.structure.identifier | Institut de psychiatrie et neurosciences de Paris [IPNP - U1266 Inserm] | |
dc.contributor.author | DUBERTRET, Caroline | |
dc.contributor.author | DUBREUCQ, Julien | |
dc.contributor.author | FOND, Guillaume | |
hal.structure.identifier | Fondation FondaMental [Créteil] | |
hal.structure.identifier | Centre d'études et de recherche sur les services de santé et la qualité de vie [CEReSS] | |
dc.contributor.author | LANÇON, Christophe | |
dc.contributor.author | LEIGNIER, Sylvain | |
dc.contributor.author | MALLET, Jasmina | |
hal.structure.identifier | Institut de Neurosciences cognitives et intégratives d'Aquitaine [INCIA] | |
hal.structure.identifier | Fondation FondaMental [Créteil] | |
hal.structure.identifier | Nutrition et Neurobiologie intégrée [NutriNeuro] | |
dc.contributor.author | MISDRAHI, David | |
dc.contributor.author | PIRES, Sylvie | |
dc.contributor.author | SCHNEIDER, Priscille | |
hal.structure.identifier | Fondation FondaMental [Créteil] | |
hal.structure.identifier | IMRB - "Neuropsychiatrie translationnelle" [Créteil] [U955 Inserm - UPEC] | |
dc.contributor.author | SCHURHOFF, Franck | |
dc.contributor.author | YAZBEK, Hanan | |
dc.contributor.author | ZINETTI-BERTSCHY, Anna | |
hal.structure.identifier | Fondation FondaMental [Créteil] | |
hal.structure.identifier | Centre de recherche en épidémiologie et santé des populations [CESP] | |
dc.contributor.author | PASSERIEUX, Christine | |
hal.structure.identifier | Fondation FondaMental [Créteil] | |
hal.structure.identifier | Centre de recherche en épidémiologie et santé des populations [CESP] | |
dc.contributor.author | BRUNET-GOUET, Eric | |
dc.date.accessioned | 2023-10-04T14:25:19Z | |
dc.date.available | 2023-10-04T14:25:19Z | |
dc.date.issued | 2023-02-01 | |
dc.identifier.uri | oai:crossref.org:10.1016/j.schres.2022.12.037 | |
dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/184330 | |
dc.description.abstractEn | Background. Social metacognition is still poorly understood in schizophrenia, particularly its neuropsychological basis and its impact on insight and medication adherence. We therefore quantified social metacognition as the agreement between objective and subjective mentalization and assessed its correlates in a sample of individuals with schizophrenia spectrum disorders. Methods. Participants consisted of 143 patients with schizophrenia or schizoaffective disorders who underwent a metacognitive version of a mentalization task, an extensive neuropsychological battery, and a clinical evaluation to assess their insight into illness and medication adherence. We studied potential interactions between confidence judgments and several neuropsychological and clinical variables on mentalization accuracy with mixed-effects multiple logistic regressions. Results. Confidence judgments were closely associated with mentalization accuracy, indicative of good social metacognition in this task. Working memory, visual memory, and reasoning and problem-solving were the three neuropsychological dimensions positively associated with metacognition. By contrast, the two measures of medication adherence were associated with poorer metacognition, whereas no association was found between metacognition and clinical insight. The multiple regression model showed a significant positive impact of better working memory, older age at onset, longer duration of hospitalization, and worse medication adherence on social metacognition. | |
dc.description.sponsorship | Sorbonne Universités à Paris pour l'Enseignement et la Recherche | en_US |
dc.description.sponsorship | FondaMental-Cohortes - ANR-10-COHO-0010 | en_US |
dc.language.iso | EN | en_US |
dc.source | crossref | |
dc.subject.en | Schizophrenia | |
dc.subject.en | Metacognition | |
dc.subject.en | Neuropsychological assessment | |
dc.subject.en | Insight | |
dc.subject.en | Medication | |
dc.subject.en | Adherence | |
dc.subject.en | Mentalization | |
dc.subject.en | Social cognition | |
dc.title.en | Relationships between neuropsychological performance, insight, medication adherence, and social metacognition in schizophrenia | |
dc.type | Document de travail - Pré-publication | en_US |
dc.identifier.doi | 10.1016/j.schres.2022.12.037 | en_US |
dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC] | en_US |
dc.identifier.pubmed | 36623435 | en_US |
dc.description.sponsorshipEurope | The motor hypothesis for self-monitoring: A new framework to understand and treat metacognitive failures | en_US |
bordeaux.journal | Schizophrenia Research | en_US |
bordeaux.page | 48-55 | en_US |
bordeaux.volume | 252 | en_US |
bordeaux.hal.laboratories | NutriNeuro (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286 | en_US |
bordeaux.institution | Université de Bordeaux | en_US |
bordeaux.institution | Bordeaux INP | en_US |
bordeaux.institution | INRAE | en_US |
bordeaux.institution | CNRS | |
bordeaux.identifier.funderID | Fondation FondaMental | en_US |
bordeaux.import.source | dissemin | |
hal.popular | non | en_US |
hal.audience | Internationale | en_US |
hal.export | false | |
workflow.import.source | dissemin | |
dc.rights.cc | Pas de Licence CC | en_US |
bordeaux.subtype | Prepublication/Preprint | en_US |
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