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The receptor kinase FERONIA regulates phosphatidylserine localization at the cell surface to modulate ROP signaling

dc.rights.licenseopenen_US
dc.contributor.authorSMOKVARSKA, Marija
dc.contributor.authorBAYLE, Vincent
dc.contributor.authorMANETA-PEYRET, Lilly
hal.structure.identifierLaboratoire de biogenèse membranaire [LBM]
dc.contributor.authorFOUILLEN, Laetitia
ORCID: 0000-0002-1204-9296
IDREF: 136936385
dc.contributor.authorPOITOUT, Arthur
dc.contributor.authorDONGOIS, Armelle
dc.contributor.authorFICHE, Jean-Bernard
dc.contributor.authorGRONNIER, Julien
dc.contributor.authorGARCIA, José
dc.contributor.authorHÖFTE, Herman
dc.contributor.authorNOLMANN, Marcelo
dc.contributor.authorZIPFEL, Cyril
dc.contributor.authorMAUREL, Christophe
hal.structure.identifierLaboratoire de biogenèse membranaire [LBM]
dc.contributor.authorMOREAU, Patrick
IDREF: 058610723
dc.contributor.authorJAILLAIS, Yvon
dc.contributor.authorMARTINIERE, Alexandre
dc.date.accessioned2023-06-29T10:25:31Z
dc.date.available2023-06-29T10:25:31Z
dc.date.issued2023-04-07
dc.identifier.issn2375-2548en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/183247
dc.description.abstractEnCells maintain a constant dialog between the extracellular matrix and their plasma membrane to fine tune signal transduction processes. We found that the receptor kinase FERONIA (FER), which is a proposed cell wall sensor, modulates phosphatidylserine plasma membrane accumulation and nano-organization, a key regulator of Rho GTPase signaling in Arabidopsis. We demonstrate that FER is required for both Rho-of-Plant 6 (ROP6) nano-partitioning at the membrane and downstream production of reactive oxygen species upon hyperosmotic stimulus. Genetic and pharmacological rescue experiments indicate that phosphatidylserine is required for a subset of, but not all, FER functions. Furthermore, application of FER ligand shows that its signaling controls both phosphatidylserine membrane localization and nanodomains formation, which, in turn, tunes ROP6 signaling. Together, we propose that a cell wall-sensing pathway controls via the regulation of membrane phospholipid content, the nano-organization of the plasma membrane, which is an essential cell acclimation to environmental perturbations.
dc.language.isoENen_US
dc.rightsAttribution-NonCommercial 3.0 United States*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/us/*
dc.subject.enArabidopsis Proteins
dc.subject.enPhosphatidylserines
dc.subject.enSignal Transduction
dc.subject.enArabidopsis
dc.subject.enPhosphotransferases
dc.subject.enCell Membrane
dc.subject.enPlants
dc.title.enThe receptor kinase FERONIA regulates phosphatidylserine localization at the cell surface to modulate ROP signaling
dc.title.alternativeSci Adven_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1126/sciadv.add4791en_US
dc.subject.halSciences du Vivant [q-bio]/Biologie végétaleen_US
dc.identifier.pubmed37027473en_US
bordeaux.journalScience Advancesen_US
bordeaux.volume9en_US
bordeaux.hal.laboratoriesLaboratoire de Biogenèse Membranaire (LBM) - UMR 5200en_US
bordeaux.issue14en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionCNRSen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcepubmed
hal.exportfalse
workflow.import.sourcepubmed
dc.rights.ccCC BY-NCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Science%20Advances&rft.date=2023-04-07&rft.volume=9&rft.issue=14&rft.eissn=2375-2548&rft.issn=2375-2548&rft.au=SMOKVARSKA,%20Marija&BAYLE,%20Vincent&MANETA-PEYRET,%20Lilly&FOUILLEN,%20Laetitia&POITOUT,%20Arthur&rft.genre=article


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