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Major depression, sleep, hostility and body mass index are associated with impaired quality of life in schizophrenia. Results from the FACE-SZ cohort.

dc.rights.licenseopenen_US
dc.contributor.authorFOND, Guillaume B.
dc.contributor.authorKORCHIA, Theo
dc.contributor.authorSUNHARY DE VERVILLE, P. L.
dc.contributor.authorGODIN, Ophelia
dc.contributor.authorSCHURHOFF, Franck
dc.contributor.authorBERNA, F.
dc.contributor.authorANDRE, Myrtille
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorAOUIZERATE, Bruno
dc.contributor.authorCAPDEVIELLE, Delphine
dc.contributor.authorCHEREAU, Isabelle
dc.contributor.authorD'AMATO, Thierry A.
dc.contributor.authorDUBERTRET, Caroline
dc.contributor.authorDUBREUCQ, Julien
dc.contributor.authorLEIGNIER, Sylvain
dc.contributor.authorMALLET, Jasmina
hal.structure.identifierInstitut de Neurosciences cognitives et intégratives d'Aquitaine [INCIA]
dc.contributor.authorMISDRAHI, David
dc.contributor.authorPASSERIEUX, Christine
dc.contributor.authorPIGNON, Baptiste
dc.contributor.authorREY, Romain
dc.contributor.authorSZOKE, Andrei
dc.contributor.authorURBACH, Mathieu
dc.contributor.authorVIDAILHET, Pierre
dc.contributor.authorLEBOYER, Marion
dc.contributor.authorLLORCA, Pierre Michel
dc.contributor.authorLANCON, Christophe
dc.contributor.authorBOYER, Laurent
dc.date.accessioned2023-05-24T10:56:20Z
dc.date.available2023-05-24T10:56:20Z
dc.date.issued2020-09-01
dc.identifier.issn0165-0327en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/182299
dc.description.abstractEnBackground: Impaired Quality of life (QoL) in schizophrenia has been mostly associated with psychotic and mood symptomatology, insight and functioning so far. Aims: QoL levels remain unsatisfactory due to other factors we aim to explore. Method: We have explored sleep quality with the Pittsburgh Sleep Quality Index, hostility with the Buss&Perry questionnaire, major depression with the Positive and Negative Syndrome Scale depressive factor, functioning with the Global Assessment of Functioning scale and weight gain with body mass index in addition to other classical QoL-associated factors. Results: 559 patients (mean age=31 (SD 9) years, 74% male sex) were included in the national FACE-SZ cohort. Impaired QoL has been significantly associated with respectively major depression, impaired sleep quality, increased hostility, impaired functioning and impaired insight independently of age, sex, treatments, tobacco smoking and body mass index. Major depression was associated with impaired psychological and physical well-being, and impaired self-esteem. Impaired sleep quality has been associated with impaired psychological and physical well-being and sentimental life. Hostility has been associated with impaired psychological well-being and self-esteem, impaired friends’ relationships and impaired autonomy. Weight was associated with impaired physical well-being. Tobacco smoking was associated with higher level of friends’ relationships. Conclusions: Major depression, sleep, hostility, and weight gain have been identified as potential targets to improve QoL in schizophrenia and should be implemented in the recommendations for good practice to optimize schizophrenia care.
dc.description.sponsorshipFondaMental-Cohortes - ANR-10-COHO-0010en_US
dc.language.isoENen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nc/
dc.subject.enMajor depression
dc.subject.enPsychiatry
dc.subject.enQuality of life
dc.subject.enSchizophrenia
dc.subject.enSleep quality
dc.subject.enWeight
dc.subject.enHostility
dc.title.enMajor depression, sleep, hostility and body mass index are associated with impaired quality of life in schizophrenia. Results from the FACE-SZ cohort.
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.jad.2020.05.003en_US
dc.subject.halSciences du Vivant [q-bio]/Médecine humaine et pathologie/Psychiatrie et santé mentaleen_US
dc.identifier.pubmed32663995en_US
bordeaux.journalJournal of Affective Disordersen_US
bordeaux.page617-623en_US
bordeaux.volume274en_US
bordeaux.hal.laboratoriesNutriNeuro (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINRAEen_US
bordeaux.institutionCNRS
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
bordeaux.import.sourcehal
hal.identifierhal-02867473
hal.version1
hal.exportfalse
workflow.import.sourcehal
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Journal%20of%20Affective%20Disorders&rft.date=2020-09-01&rft.volume=274&rft.spage=617-623&rft.epage=617-623&rft.eissn=0165-0327&rft.issn=0165-0327&rft.au=FOND,%20Guillaume%20B.&KORCHIA,%20Theo&SUNHARY%20DE%20VERVILLE,%20P.%20L.&GODIN,%20Ophelia&SCHURHOFF,%20Franck&rft.genre=article


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