High SARS-CoV-2 seroprevalence among street adolescents in Lome, Togo, 2021
| dc.rights.license | open | en_US |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | SADIO, Arnold Junior | |
| dc.contributor.author | FERRE, Valentine Marie | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| hal.structure.identifier | Global Health in the Global South [GHiGS] | |
| dc.contributor.author | KONU, Rodion Yao | |
| dc.contributor.author | DAGNRA, Anoumou Claver | |
| dc.contributor.author | DESCAMPS, Diane | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| hal.structure.identifier | Global Health in the Global South [GHiGS] | |
| dc.contributor.author | EKOUEVI, Didier Koumavi | |
| dc.contributor.author | CHARPENTIER, Charlotte | |
| dc.date.accessioned | 2023-05-15T12:00:54Z | |
| dc.date.available | 2023-05-15T12:00:54Z | |
| dc.date.issued | 2023-04-03 | |
| dc.identifier.issn | 1471-2334 | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/182134 | |
| dc.description.abstractEn | BACKGROUND: There is almost no data on the circulation of SARS-CoV-2 among street adolescents. We conducted a study to document the immunization status of street adolescents in Togo against different variants of SARS-CoV-2. METHODS: A cross-sectional study was carried out in 2021 in Lomé, the city with the highest number of COVID 19 cases in Togo (60%). Adolescents aged 13- and 19 years old living on the street were eligible for inclusion. A standardized questionnaire was administered face-to-face to adolescents. A sample of blood was taken and aliquots of plasma were transported to the virology laboratory of the Hôpital Bichat-Claude Bernard (Paris, France). SARS-CoV-2 anti-S and anti-N IgG were measured using chemiluminescent microparticle immunoassay. A quantitative miniaturized and parallel-arranged ELISA assay was used to detect IgG antibodies specifically directed against the different SARS-CoV-2 Variants of Concern (VOC). RESULTS: A total of 299 street adolescents (5.2% female), median age 15 years, interquartile range (14-17 years), were included in this study. The prevalence of SARS-CoV-2 infection was 63.5% (95%CI: 57.8-69.0). Specific-IgG against the ancestral Wuhan strain was developed by 92.0% of subjects. The proportion of patients being immunized against each VOC was 86.8%, 51.1%, 56.3%, 60.0, and 30.5% for the Alpha, Beta, Gamma, Delta, and Omicron VOCs, respectively. CONCLUSION: This study showed a very high prevalence with approximately 2/3 of Togolese street adolescents having antibodies to SARS-CoV-2 due to a previous infection. These results confirm an under-reporting of COVID-19 cases in Togo, questioning the hypothesis of low virus circulation in Togo and even in Africa. | |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.subject.en | SARS-CoV-2 seroprevalence | |
| dc.subject.en | Street adolescents | |
| dc.subject.en | Togo | |
| dc.title.en | High SARS-CoV-2 seroprevalence among street adolescents in Lome, Togo, 2021 | |
| dc.title.alternative | BMC Infect Dis | en_US |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1186/s12879-023-08167-2 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 37013507 | en_US |
| bordeaux.journal | BMC Infectious Diseases | en_US |
| bordeaux.volume | 23 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.issue | 1 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | GHIGS_BPH | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| hal.identifier | hal-04097650 | |
| hal.version | 1 | |
| hal.date.transferred | 2023-05-15T12:01:07Z | |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=BMC%20Infectious%20Diseases&rft.date=2023-04-03&rft.volume=23&rft.issue=1&rft.eissn=1471-2334&rft.issn=1471-2334&rft.au=SADIO,%20Arnold%20Junior&FERRE,%20Valentine%20Marie&KONU,%20Rodion%20Yao&DAGNRA,%20Anoumou%20Claver&DESCAMPS,%20Diane&rft.genre=article |
