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dc.contributor.authorMURRELL, Michael
dc.contributor.authorPONTANI, Lea-Laetitia
dc.contributor.authorGUEVORKIAN, Karine
dc.contributor.authorCUVELIER, Damien
hal.structure.identifierlp2n-04,lp2n-16
dc.contributor.authorNASSOY, Pierre
dc.contributor.authorSYKES, C.
dc.date.accessioned2023-05-12T10:22:38Z
dc.date.available2023-05-12T10:22:38Z
dc.date.created2010-10-01
dc.date.issued2011-03-16
dc.identifier.issn0006-3495
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/181152
dc.description.abstractEnReconstituted systems mimicking cells are interesting tools for understanding the details of cell behavior. Here, we use an experimental system that mimics cellular actin cortices, namely liposomes developing an actin shell close to their inner membrane, and we study their dynamics of spreading. We show that depending on the morphology of the actin shell inside the liposome, spreading dynamics is either reminiscent of a bare liposome (in the case of a sparse actin shell) or of a cell (in the case of a continuous actin shell). We use a mechanical model that qualitatively accounts for the shape of the experimental curves. From the data on spreading dynamics, we extract characteristic times that are consistent with mechanical estimates. The mechanical characterization of such stripped-down experimental systems paves the way for a more complex design closer to a cell. We report here the first step in building an artificial cell and studying its mechanics.
dc.language.isoen
dc.publisherBiophysical Society
dc.subject.enCELLS
dc.subject.enMEMBRANES
dc.subject.enADHESION
dc.subject.enVESICLES
dc.subject.enMECHANICS
dc.subject.enSHAPE
dc.title.enSpreading Dynamics of Biomimetic Actin Cortices
dc.typeArticle de revue
dc.subject.halPhysique [physics]/Physique [physics]/Biophysique [physics.bio-ph]
bordeaux.journalBiophysical Journal
bordeaux.page1400-1409
bordeaux.volume100
bordeaux.hal.laboratoriesLaboratoire Photonique, Numérique et Nanosciences (LP2N) - UMR 5298*
bordeaux.issue6
bordeaux.institutionUniversité de Bordeaux
bordeaux.institutionCNRS
bordeaux.peerReviewedoui
hal.identifierhal-00821326
hal.version1
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-00821326v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Biophysical%20Journal&rft.date=2011-03-16&rft.volume=100&rft.issue=6&rft.spage=1400-1409&rft.epage=1400-1409&rft.eissn=0006-3495&rft.issn=0006-3495&rft.au=MURRELL,%20Michael&PONTANI,%20Lea-Laetitia&GUEVORKIAN,%20Karine&CUVELIER,%20Damien&NASSOY,%20Pierre&rft.genre=article


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