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hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorERCICEK, Fatma
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorHARSCOAT-SCHIAVO, Christelle
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorMARCHIVIE, Mathieu
hal.structure.identifierInstitut de Chimie de la Matière Condensée de Bordeaux [ICMCB]
dc.contributor.authorMARRE, Samuel
hal.structure.identifierChimie et Biologie des Membranes et des Nanoobjets [CBMN]
dc.contributor.authorSUBRA-PATERNAULT, Pascale
dc.date.conference2022-08-31
dc.description.abstractEnCo-crystalline products are becoming increasingly important in the pharmaceutical industry, due to the chirality, low water solubility and low bioavailability of most active pharmaceutical ingredients (API). Solids with a single crystalline phase composed of two entities (API + coformer COF) linked via non-covalent interactions are called co-crystals. The modification of the API crystal lattice through the incorporation of the COF enhances the physicochemical properties of the initial drug without altering its therapeutic purposes. Thus, understanding crystallization processes can help to obtain products with desired properties. The formation of metastable conglomerates by co-crystallization can be a solution for optical resolution
dc.description.sponsorshipApport du CO2 dans le contrôle de phase cristalline - ANR-18-CE07-0047
dc.language.isoen
dc.rights.urihttp://creativecommons.org/licenses/by/
dc.source.titleProceedings 27th International Workshop on Industrial Crystallization
dc.subject.enCo-crystallization
dc.subject.enSupercritical CO2
dc.subject.enChiral resolution
dc.subject.enIn-situ observations
dc.subject.enMicrofluidics
dc.title.enInvestigations of pharmaceutical compounds co-crystallization for application to chiral resolution assisted by supercritical CO2
dc.typeCommunication dans un congrès
dc.subject.halSciences de l'ingénieur [physics]
dc.subject.halSciences de l'ingénieur [physics]/Génie des procédés
bordeaux.countryFI
bordeaux.title.proceedingProceedings 27th International Workshop on Industrial Crystallization
bordeaux.conference.cityEspoo
bordeaux.peerReviewedoui
hal.identifierhal-03718287
hal.version1
hal.invitednon
hal.proceedingsoui
hal.conference.end2022-09-02
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-03718287v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.btitle=Proceedings%2027th%20International%20Workshop%20on%20Industrial%20Crystallization&rft.au=ERCICEK,%20Fatma&HARSCOAT-SCHIAVO,%20Christelle&MARCHIVIE,%20Mathieu&MARRE,%20Samuel&SUBRA-PATERNAULT,%20Pascale&rft.genre=unknown


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