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The effect of the 7R allele on the DRD4 risk tolerance locus is independent of background risk in Senegalese fishermen

hal.structure.identifierCentre de Recherche en Économie et Statistique [CREST]
dc.contributor.authorCLOCHARD, Gwen-Jiro
hal.structure.identifierUniversité Gaston Berger de Saint-Louis Sénégal [UGB]
dc.contributor.authorMBENGUE, Aby
hal.structure.identifierInstitut de génétique humaine [IGH]
dc.contributor.authorMETTLING, Clément
hal.structure.identifierUniversité Gaston Berger de Saint-Louis Sénégal [UGB]
dc.contributor.authorDIOUF, Birane
hal.structure.identifierInstitut des Sciences de l'Evolution de Montpellier [UMR ISEM]
dc.contributor.authorFAURIE, Charlotte
hal.structure.identifierUniversité Alioune Diop de Bambey [UADB]
dc.contributor.authorSENE, Omar
hal.structure.identifierBiodiversité, Gènes & Communautés [BioGeCo]
dc.contributor.authorCHANCEREL, Emilie
hal.structure.identifierBiodiversité, Gènes & Communautés [BioGeCo]
dc.contributor.authorGUICHOUX, Erwan
hal.structure.identifierÉcole polytechnique [X]
dc.contributor.authorHOLLARD, Guillaume
hal.structure.identifierInstitut des Sciences de l'Evolution de Montpellier [UMR ISEM]
dc.contributor.authorRAYMOND, Michel
hal.structure.identifierCentre d'Economie de l'Environnement - Montpellier [CEE-M]
dc.contributor.authorWILLINGER, Marc
dc.date.issued2023
dc.identifier.issn2045-2322
dc.description.abstractEnIt has been shown that living in risky environments, as well as having a risky occupation, can moderate risk-tolerance. Despitethe involvement of dopamine in the expectation of reward described by neurobiologists, a GWAS study was not able todemonstrate a genetic contribution of genes involved in the dopaminergic pathway in risk attitudes and gene candidate studiesgave contrasting results. We test the possibility that a genetic effect of the DRD4-7R allele in risk-taking behavior could bemodulated by environmental factors. We show that the increase in risk-tolerance due to the 7R allele is independent of theenvironmental risk in two populations in Northern Senegal, one of which is exposed to a very high risk due to dangerous fishing.
dc.language.isoen
dc.publisherNature Publishing Group
dc.rights.urihttp://creativecommons.org/licenses/by/
dc.title.enThe effect of the 7R allele on the DRD4 risk tolerance locus is independent of background risk in Senegalese fishermen
dc.typeArticle de revue
dc.identifier.doi10.21203/rs.3.rs-1968350/v1
dc.subject.halSciences de l'Homme et Société
dc.subject.halSciences de l'Homme et Société/Economies et finances
bordeaux.journalScientific Reports
bordeaux.volume13 (622)
bordeaux.peerReviewedoui
hal.identifierhal-03930527
hal.version1
hal.popularnon
hal.audienceInternationale
hal.origin.linkhttps://hal.archives-ouvertes.fr//hal-03930527v1
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Scientific%20Reports&rft.date=2023&rft.volume=13%20(622)&rft.eissn=2045-2322&rft.issn=2045-2322&rft.au=CLOCHARD,%20Gwen-Jiro&MBENGUE,%20Aby&METTLING,%20Cl%C3%A9ment&DIOUF,%20Birane&FAURIE,%20Charlotte&rft.genre=article


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