Forgetting in obesity: The pregnenolone link
| dc.rights.license | open | en_US |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | BELLOCCHIO, Luigi | |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | MARSICANO, Giovanni | |
| dc.date.accessioned | 2023-03-28T16:36:11Z | |
| dc.date.available | 2023-03-28T16:36:11Z | |
| dc.date.created | 2022 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/172643 | |
| dc.description.abstractEn | Cognitive dysfunction is often diagnosed in people with obesity and associated metabolic disorders. In the latest issue of Cell Metabolism, Ramírez et al. highlight an impaired production of the neurosteroid pregnenolone in the hypothalamus as a mechanism for obesity-induced cognitive impairment in both rodent models and patients with obesity. | |
| dc.description.sponsorship | Dissection des mécanismes hypothalamiques impliqués dans la détection du statut nutritionnel et régulation de la prise alimentaire via les interactions entre mTORC1, les mélanocortines et les endocannabinoïdes. - ANR-13-BSV4-0006 | en_US |
| dc.description.sponsorship | Représentation sensorielle lors d'états psychotiques - ANR-16-CE37-0010 | en_US |
| dc.description.sponsorship | Role du recepteur CB1 mitocondriel du tissue adipeux dans la regulation de la balance energetique - ANR-19-CE14-0039 | en_US |
| dc.description.sponsorship | Bordeaux Region Aquitaine Initiative for Neuroscience - ANR-10-LABX-0043 | en_US |
| dc.language.iso | EN | en_US |
| dc.subject.en | Pregnenolone | |
| dc.subject.en | Complication | |
| dc.subject.en | Human | |
| dc.subject.en | Hypothalamus | |
| dc.subject.en | Obesity | |
| dc.subject.en | Humans | |
| dc.title.en | Forgetting in obesity: The pregnenolone link | |
| dc.title.alternative | Cell Metab | en_US |
| dc.type | Document de travail - Pré-publication | en_US |
| dc.identifier.doi | 10.1016/j.cmet.2022.01.006 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC] | en_US |
| dc.identifier.pubmed | 35108507 | en_US |
| dc.description.sponsorshipEurope | Neurocircuitry of endocannabinoid regulation of food intake | en_US |
| dc.description.sponsorshipEurope | Development of pregnenolone derivatives as allosteric inhibitors of CB1 cannabinoid receptors for thetreatment of schizophrenia and psychotic syndromes | en_US |
| bordeaux.page | 187 | en_US |
| bordeaux.hal.laboratories | Neurocentre Magendie - U1215 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | Endocannabinoïdes et Neuroadaptation | en_US |
| bordeaux.identifier.funderID | Fondation pour la Recherche Médicale | en_US |
| bordeaux.identifier.funderID | Human Frontier Science Program | en_US |
| bordeaux.identifier.funderID | Conseil Régional Aquitaine | en_US |
| hal.identifier | hal-04049696 | |
| hal.version | 1 | |
| hal.date.transferred | 2023-03-28T16:36:14Z | |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.spage=187&rft.epage=187&rft.au=BELLOCCHIO,%20Luigi&MARSICANO,%20Giovanni&rft.genre=preprint |
