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Metabolic Messengers: endocannabinoids
| dc.rights.license | open | en_US |
| hal.structure.identifier | IMIM-Hospital del Mar | |
| dc.contributor.author | BUSQUETS-GARCIA, Arnau | |
| hal.structure.identifier | Universidad de Salamanca [España] = University of Salamanca [Spain] | |
| hal.structure.identifier | Instituto de Biología Funcional y Genómica [Salamanca, Spain] [IBFG] | |
| dc.contributor.author | BOLAÑOS, Juan P. | |
| hal.structure.identifier | Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale [U1215 Inserm - UB] | |
| dc.contributor.author | MARSICANO, Giovanni | |
| dc.date.accessioned | 2023-03-27T14:52:21Z | |
| dc.date.available | 2023-03-27T14:52:21Z | |
| dc.date.created | 2022 | |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/172632 | |
| dc.description.abstractEn | The endocannabinoid system is considered one of the most important modulatory networks in the whole organism. Research has yielded great insight on the mechanisms that link endocannabinoids and several peripheral and brain metabolic functions. Here, we provide a brief overview of the metabolic roles of endocannabinoids in tissue-, cellular- and subcellular-dependent mechanisms. We highlight past discoveries and future open questions with a special focus on CB1 receptor-dependent astroglial and mitochondrial metabolic processes. | |
| dc.description.sponsorship | Dissection des mécanismes hypothalamiques impliqués dans la détection du statut nutritionnel et régulation de la prise alimentaire via les interactions entre mTORC1, les mélanocortines et les endocannabinoïdes. - ANR-13-BSV4-0006 | en_US |
| dc.description.sponsorship | Représentation sensorielle lors d'états psychotiques - ANR-16-CE37-0010 | en_US |
| dc.description.sponsorship | Bordeaux Region Aquitaine Initiative for Neuroscience - ANR-10-LABX-0043 | en_US |
| dc.language.iso | EN | en_US |
| dc.subject.en | Biochemical Phenomena | |
| dc.subject.en | Central Nervous System | |
| dc.subject.en | Endocannabinoids | |
| dc.subject.en | Signal Transduction | |
| dc.subject.en | Cannabinoid 1 receptor | |
| dc.subject.en | Endocannabinoid | |
| dc.subject.en | Mammalian target of rapamycin | |
| dc.subject.en | Messenger RNA | |
| dc.subject.en | Mitogen activated protein kinase | |
| dc.subject.en | Phospholipase C | |
| dc.subject.en | Protein kinase B | |
| dc.subject.en | Protein p53 | |
| dc.subject.en | Rho guanine nucleotide binding protein | |
| dc.subject.en | Adipose tissue | |
| dc.subject.en | Aerobic metabolism | |
| dc.subject.en | Brain | |
| dc.subject.en | cAMP signaling | |
| dc.subject.en | Cannabis sativa | |
| dc.subject.en | Drug degradation | |
| dc.subject.en | Drug synthesis | |
| dc.subject.en | Energy metabolism | |
| dc.subject.en | Fatty liver | |
| dc.subject.en | Glucose transport | |
| dc.subject.en | Homeostasis | |
| dc.subject.en | Liver | |
| dc.subject.en | Metabolic messenger | |
| dc.subject.en | Oxidative phosphorylation | |
| dc.subject.en | Oxygen consumption | |
| dc.subject.en | Protein expression | |
| dc.subject.en | Signal transduction | |
| dc.subject.en | Biochemistry | |
| dc.subject.en | Central nervous system | |
| dc.subject.en | Signal transduction | |
| dc.title.en | Metabolic Messengers: endocannabinoids | |
| dc.title.alternative | Nat Metab | en_US |
| dc.type | Document de travail - Pré-publication | en_US |
| dc.identifier.doi | 10.1038/s42255-022-00600-1 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC] | en_US |
| dc.identifier.pubmed | 35817852 | en_US |
| dc.description.sponsorshipEurope | Neurocircuitry of endocannabinoid regulation of food intake | en_US |
| dc.description.sponsorshipEurope | Development of pregnenolone derivatives as allosteric inhibitors of CB1 cannabinoid receptors for thetreatment of schizophrenia and psychotic syndromes | en_US |
| bordeaux.page | 848 | en_US |
| bordeaux.hal.laboratories | Neurocentre Magendie - U1215 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | Endocannabinoïdes et Neuroadaptation | en_US |
| bordeaux.identifier.funderID | Agencia Estatal de Investigación | en_US |
| bordeaux.identifier.funderID | Fondation pour la Recherche Médicale | en_US |
| bordeaux.identifier.funderID | Conseil Régional Aquitaine | en_US |
| hal.identifier | hal-04048082 | |
| hal.version | 1 | |
| hal.date.transferred | 2023-03-27T14:52:29Z | |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.spage=848&rft.epage=848&rft.au=BUSQUETS-GARCIA,%20Arnau&BOLA%C3%91OS,%20Juan%20P.&MARSICANO,%20Giovanni&rft.genre=preprint |
