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Early-life factors associated with increased risk of disability pension in the national real-world schizophrenia FACE-SZ cohort study

dc.rights.licenseopenen_US
hal.structure.identifierFondation FondaMental [Créteil]
dc.contributor.authorFOND, Guillaume
hal.structure.identifierFondation FondaMental [Créteil]
dc.contributor.authorDUBREUCQ, Julien
dc.contributor.authorDE VERVILLE, P.L.S.
hal.structure.identifierFondation FondaMental [Créteil]
dc.contributor.authorGODIN, Ophelia
dc.contributor.authorANDRIEU-HALLER, C.
dc.contributor.authorBERNA, F.
hal.structure.identifierInstitut de Neurosciences cognitives et intégratives d'Aquitaine [INCIA]
hal.structure.identifierFondation FondaMental [Créteil]
hal.structure.identifierNutrition et Neurobiologie intégrée [NutriNeuro]
dc.contributor.authorAOUIZERATE, Bruno
dc.contributor.authorCAPDEVIELLE, D.
dc.contributor.authorCHEREAU, I.
dc.contributor.authorCLAUSS-KOBAYASHI, J.
dc.contributor.authorCOULON, N.
dc.contributor.authorDOREY, J.M.
dc.contributor.authorDUBERTRET, C.
dc.contributor.authorMALLET, J.
hal.structure.identifierInstitut de Neurosciences cognitives et intégratives d'Aquitaine [INCIA]
hal.structure.identifierFondation FondaMental [Créteil]
dc.contributor.authorMISDRAHI, David
dc.contributor.authorPASSERIEUX, C.
dc.contributor.authorREY, R.
dc.contributor.authorPIGNON, B.
dc.contributor.authorSCHÜRHOFF, F.
dc.contributor.authorURBACH, M.
dc.contributor.authorLLORCA, P.M.
dc.contributor.authorLANÇON, C.
dc.contributor.authorBOYER, L.
dc.date.accessioned2023-02-27T10:23:32Z
dc.date.available2023-02-27T10:23:32Z
dc.date.issued2022-03-25
dc.identifier.issn0940-1334en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/172099
dc.description.abstractEnAmong severe psychiatric disorders, schizophrenia has one of the highest impacts on professional and personal functioning with important indirect costs including disability pension allowance for the patients with the more severe forms of schizophrenia. To explore early-life factors associated with disability pension in schizophrenia. 916 patients were consecutively recruited at a national level in 10 expert centers and received a comprehensive standardized evaluation. Their disability pension status and early-life variables were reported from medical records and validated scales. Eight factors were explored: age, male sex, parental history of severe mental illness, childhood trauma exposure, education level, childhood ADHD, early age at schizophrenia onset and duration of untreated psychosis. 739 (80.7%) participants received a disability pension. In the multivariate model, early age at schizophrenia onset and low education level were associated with disability pension independently of age and sex while no significant association was found for parent history of severe mental illness, childhood trauma, childhood ADHD or duration of untreated psychosis. Low education level and early age at schizophrenia onset seem the best predictors of increased risk of disability pension in schizophrenia. © 2022, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany.
dc.language.isoENen_US
dc.subject.enMental health
dc.subject.enPsychiatry
dc.subject.enSchizophrenia
dc.subject.enQuality of life
dc.subject.enPublic health
dc.title.enEarly-life factors associated with increased risk of disability pension in the national real-world schizophrenia FACE-SZ cohort study
dc.typeArticle de revueen_US
dc.identifier.doi10.1007/s00406-021-01364-7en_US
dc.subject.halSciences du Vivant [q-bio]/Neurosciences [q-bio.NC]en_US
dc.identifier.pubmed35333961en_US
bordeaux.journalEuropean archives of psychiatry and clinical neuroscienceen_US
bordeaux.page1379-1384en_US
bordeaux.volume272en_US
bordeaux.hal.laboratoriesNutriNeurO (Laboratoire de Nutrition et Neurobiologie Intégrée) - UMR 1286en_US
bordeaux.issue7en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionINRAEen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
hal.exportfalse
dc.rights.ccPas de Licence CCen_US
bordeaux.COinSctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=European%20archives%20of%20psychiatry%20and%20clinical%20neuroscience&rft.date=2022-03-25&rft.volume=272&rft.issue=7&rft.spage=1379-1384&rft.epage=1379-1384&rft.eissn=0940-1334&rft.issn=0940-1334&rft.au=FOND,%20Guillaume&DUBREUCQ,%20Julien&DE%20VERVILLE,%20P.L.S.&GODIN,%20Ophelia&ANDRIEU-HALLER,%20C.&rft.genre=article


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