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dc.rights.licenseopenen_US
hal.structure.identifierInstitut de Mécanique et d'Ingénierie [I2M]
dc.contributor.authorURCUN, Stéphane
dc.contributor.authorROHAN, Pierre-Yves
hal.structure.identifierInstitut de Mécanique et d'Ingénierie [I2M]
dc.contributor.authorSCIUMÈ, Giuseppe
dc.contributor.authorBORDAS, Stéphane P. A.
dc.date.accessioned2023-02-06T09:49:45Z
dc.date.available2023-02-06T09:49:45Z
dc.date.issued2022-02-01
dc.identifier.issn1751-6161en_US
dc.identifier.urihttps://oskar-bordeaux.fr/handle/20.500.12278/171868
dc.description.abstractEnThis paper investigates the complex time-dependent behavior of cortex tissue, under adiabatic condition, using a two-phase flow poroelastic model. Motivated by experiments and Biot’s consolidation theory, we tackle time-dependent uniaxial loading, confined and unconfined, with various geometries and loading rates from 1μm/s to 100μm/s. The cortex tissue is modeled as the porous solid saturated by two immiscible fluids, with dynamic viscosities separated by four orders, resulting in two different characteristic times. These are respectively associated to interstitial fluid and glial cells. The partial differential equations system is discretized in space by the finite element method and in time by Euler-implicit scheme. The solution is computed using a monolithic scheme within the open-source computational framework FEniCS. The parameters calibration is based on Sobol sensitivity analysis, which divides them into two groups: the tissue specific group, whose parameters represent general properties, and sample specific group, whose parameters have greater variations. Our results show that the experimental curves can be reproduced without the need to resort to viscous solid effects, by adding an additional fluid phase. Through this process, we aim to present multiphase poromechanics as a promising way to a unified brain tissue modeling framework in a variety of settings.
dc.language.isoENen_US
dc.subject.enBrain tissue
dc.subject.enMechanical testing
dc.subject.enPoromechanics
dc.title.enCortex tissue relaxation and slow to medium load rates dependency can be captured by a two-phase flow poroelastic model
dc.title.alternativeJournal of the Mechanical Behavior of Biomedical Materialsen_US
dc.typeArticle de revueen_US
dc.identifier.doi10.1016/j.jmbbm.2021.104952en_US
dc.subject.halSciences de l'ingénieur [physics]/Matériauxen_US
bordeaux.journalJournal of the mechanical behavior of biomedical materialsen_US
bordeaux.volume126en_US
bordeaux.hal.laboratoriesInstitut de Mécanique et d’Ingénierie de Bordeaux (I2M) - UMR 5295en_US
bordeaux.institutionUniversité de Bordeauxen_US
bordeaux.institutionBordeaux INPen_US
bordeaux.institutionCNRSen_US
bordeaux.institutionINRAEen_US
bordeaux.institutionArts et Métiersen_US
bordeaux.peerReviewedouien_US
bordeaux.inpressnonen_US
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dc.rights.ccPas de Licence CCen_US
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