Maternal pre-pregnancy obesity and offspring hyperactivity-inattention symptoms at 5 years in preterm and term children: a multi-cohort analysis
| dc.rights.license | open | en_US |
| dc.contributor.author | DOW, Courtney | |
| dc.contributor.author | LORTHE, Elsa | |
| dc.contributor.author | MARCHAND-MARTIN, Laetitia | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | GALERA, Cedric | |
| dc.contributor.author | TAFFLET, Muriel | |
| dc.contributor.author | ANCEL, Pierre-Yves | |
| dc.contributor.author | CHARLES, Marie-Aline | |
| dc.contributor.author | HEUDE, Barbara | |
| dc.date.accessioned | 2022-12-15T10:25:25Z | |
| dc.date.available | 2022-12-15T10:25:25Z | |
| dc.date.issued | 2022-10-28 | |
| dc.identifier.issn | 2045-2322 (Electronic) 2045-2322 (Linking) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/171534 | |
| dc.description.abstractEn | The objective of this study was to determine the relationship between maternal pre-pregnancy body mass index (BMI) and child hyperactivity-inattention symptoms (HIS) at 5 years, including preterm and term-born children, and to determine whether this association varied with gestational age. Maternal pre-pregnancy BMI and offspring HIS were assessed in 10,898 participants born >/= 33 weeks of gestation from the ELFE cohort and 2646 children born between 23 and 34 weeks from the EPIPAGE 2 cohort. Reported pre-pregnancy weight (kg) and measured height (m) were collected from mothers at inclusion and used to classify BMI (kg/m(2)). Child HIS were evaluated using the Strengths and Difficulties Questionnaire around 5 years of age. Logistic regression estimated odds ratios (OR) of a high HIS score (>/= 90th percentile) in the ELFE cohort and generalized estimated equations were used in EPIPAGE 2 to account for non-independence of multiple births. As a negative control, paternal BMI was also considered as an exposure of interest in sensitivity analyses. Maternal pre-pregnancy obesity and overweight were associated with child HIS at 5 years in ELFE (adjusted OR [aOR] for obesity 1.27 [1.06, 1.53]; overweight aOR 1.16 [1.00, 1.36]) and pre-pregnancy obesity was associated with high HIS scores in preterm infants of EPIPAGE 2 (aOR 1.48 [1.06, 2.08]). In ELFE, the magnitude of the association increased with decreasing gestational age (interaction p = 0.02). High maternal pre-pregnancy BMI is associated with greater likelihood of high HIS scores in both at-term and preterm children at 5 years of age. | |
| dc.description.sponsorship | Plateforme de REcherche sur les COhortes d'enfants suivis depuis la NAIssance | en_US |
| dc.description.sponsorship | Maladie Rénale Chronique - Réseau Epidémiologie et Information en Néphrologie - ANR-10-COHO-0001 | en_US |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.title.en | Maternal pre-pregnancy obesity and offspring hyperactivity-inattention symptoms at 5 years in preterm and term children: a multi-cohort analysis | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1038/s41598-022-22750-8 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 36307528 | en_US |
| bordeaux.journal | Scientific Reports | en_US |
| bordeaux.page | 18190 | en_US |
| bordeaux.volume | 12 | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.issue | 1 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | HEALTHY_BPH | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.identifier.funderID | Fondation pour la Recherche Médicale | en_US |
| bordeaux.identifier.funderID | Fondation de France | en_US |
| bordeaux.identifier.funderID | Institut National de la Santé et de la Recherche Médicale | en_US |
| hal.identifier | hal-03900360 | |
| hal.version | 1 | |
| hal.date.transferred | 2022-12-15T10:25:28Z | |
| hal.export | true | |
| dc.rights.cc | Pas de Licence CC | en_US |
| bordeaux.COinS | ctx_ver=Z39.88-2004&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.jtitle=Scientific%20Reports&rft.date=2022-10-28&rft.volume=12&rft.issue=1&rft.spage=18190&rft.epage=18190&rft.eissn=2045-2322%20(Electronic)%202045-2322%20(Linking)&rft.issn=2045-2322%20(Electronic)%202045-2322%20(Linking)&rft.au=DOW,%20Courtney&LORTHE,%20Elsa&MARCHAND-MARTIN,%20Laetitia&GALERA,%20Cedric&TAFFLET,%20Muriel&rft.genre=article |
