Association between COVID-19 infection and work exposure assessed by the Mat-O-Covid job exposure matrix in the CONSTANCES cohort
| dc.rights.license | open | en_US |
| dc.contributor.author | FADEL, Marc | |
| dc.contributor.author | GILBERT, Fabien | |
| dc.contributor.author | LEGEAY, Clement | |
| dc.contributor.author | DUBEE, Vincent | |
| dc.contributor.author | ESQUIROL, Yolande | |
| hal.structure.identifier | Bordeaux population health [BPH] | |
| dc.contributor.author | VERDUN-ESQUER, Catherine | |
| dc.contributor.author | DINH, Aurelien | |
| dc.contributor.author | SEMBAJWE, Grace | |
| dc.contributor.author | GOLDBERG, Marcel | |
| dc.contributor.author | ROQUELAURE, Yves | |
| dc.contributor.author | LECLERC, Annette | |
| dc.contributor.author | WIERNIK, Emmanuel | |
| dc.contributor.author | ZINS, Marie | |
| dc.contributor.author | DESCATHA, Alexis | |
| dc.date.accessioned | 2022-10-31T14:09:24Z | |
| dc.date.available | 2022-10-31T14:09:24Z | |
| dc.date.issued | 2022-09-20 | |
| dc.identifier.issn | 1470-7926 (Electronic) 1351-0711 (Linking) | en_US |
| dc.identifier.uri | https://oskar-bordeaux.fr/handle/20.500.12278/170177 | |
| dc.description.abstractEn | OBJECTIVES: The COVID-19 pandemic has brought to light a new occupational health threat. We aimed to evaluate the association between COVID-19 infection and work exposure to SARS-CoV-2 assessed by a job-exposure matrix (JEM), in a large population cohort. We also estimated the population-attributable fraction among exposed subjects. METHODS: We used the SAPRIS-SERO sample of the CONSTANCES cohort, limited to subjects actively working, and with a job code available and a questionnaire on extra work activities. The following outcomes were assessed: COVID-19 diagnosis was made by a physician; a seropositivity to the ELISA-S test ('serology strict') and ELISA-S test intermediate with positive ELISA-NP or a positive neutralising antibodies SN ('serology large'). Job exposure was assessed using Mat-O-Covid, an expert-based JEM with an Index used as a continuous variable and a threshold at 13/1000. RESULTS: The sample included 18 999 subjects with 389 different jobs, 47.7% were men with a mean age of 46.2 years (±9.2 years). The Mat-O-Covid index taken as a continuous variable or with a threshold greater than 13/1000 was associated with all the outcomes in bivariable and multivariable logistic models. ORs were between 1.30 and 1.58, and proportion of COVID-19 attributable to work among exposed participants was between 20% and 40%. DISCUSSION: Using the Mat-O-Covid JEM applied to a large population, we found a significant association between work exposure to SARS-CoV-2 and COVID-19 infection, though the estimation of attributable fraction among exposed people remained low to moderate. Further studies during other exposed periods and with other methods are necessary. | |
| dc.description.sponsorship | La cohorte CONSTANCES - Infrastructure épidémiologique ouverte pour la recherche et la surveillance | en_US |
| dc.description.sponsorship | Etude Epidémiologique des Enfants de femmes de l'Education Nationale | en_US |
| dc.language.iso | EN | en_US |
| dc.rights | Attribution 3.0 United States | * |
| dc.rights.uri | http://creativecommons.org/licenses/by/3.0/us/ | * |
| dc.title.en | Association between COVID-19 infection and work exposure assessed by the Mat-O-Covid job exposure matrix in the CONSTANCES cohort | |
| dc.type | Article de revue | en_US |
| dc.identifier.doi | 10.1136/oemed-2022-108436 | en_US |
| dc.subject.hal | Sciences du Vivant [q-bio]/Santé publique et épidémiologie | en_US |
| dc.identifier.pubmed | 36126974 | en_US |
| bordeaux.journal | Occupational and Environmental Medicine | en_US |
| bordeaux.hal.laboratories | Bordeaux Population Health Research Center (BPH) - UMR 1219 | en_US |
| bordeaux.institution | Université de Bordeaux | en_US |
| bordeaux.institution | INSERM | en_US |
| bordeaux.team | EPICENE_BPH | en_US |
| bordeaux.peerReviewed | oui | en_US |
| bordeaux.inpress | non | en_US |
| bordeaux.identifier.funderID | Institut National de la Santé et de la Recherche Médicale | en_US |
| bordeaux.identifier.funderID | Agence Nationale de Recherches sur le Sida et les Hépatites Virales | en_US |
| bordeaux.identifier.funderID | Conseil Régional des Pays de la Loire | en_US |
| bordeaux.identifier.funderID | Angers Loire Métropole | en_US |
| bordeaux.identifier.funderID | Universite Angers | en_US |
| bordeaux.identifier.funderID | Agence Nationale de la Recherche | en_US |
| bordeaux.identifier.funderID | Merck Sharp and Dohme | en_US |
| bordeaux.identifier.funderID | AstraZeneca | en_US |
| bordeaux.identifier.funderID | Inserm Transfert | en_US |
| hal.identifier | inserm-03782693 | |
| hal.version | 1 | |
| hal.export | false | |
| dc.rights.cc | Pas de Licence CC | en_US |
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